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Efficacy of acute medication matters beyond just treating a single migraine. It may increase the risk of worsened disease.

These agents lower cholesterol and prevent cardiovascular disease, but they may actually increase the risk of Parkinson disease. Caution advised.

The ultimate cause is found in only about half of patients, so improved understanding of the prognostic and diagnostic features is of high priority.

This treatment may be superior to current treatment for patients with severe multiple sclerosis that is not responding well to standard treatments.

Drugs often involve multiple daily doses with complex dosing regimens, but interventions that have been applied generically to patients with chronic diseases can be applied to these cases as well.

Favorable long-term results for patients with hard-to-treat epilepsy who undergo brain surgery offer good information for decision-making and counseling.

There is no approved screening tool for misophonia, but a case review can lead to a diagnosis. Several treatment options may aid in symptom management.

Scientists are testing alternative therapeutic approaches that may delay disease progression and even protect and regenerate neurons.

Anticholinergics could confer an increased risk, one dependent on the dose and amount of use. Give them to older patients or consider alternatives?

Symptoms occur in nearly 1 in 5 adults who have epilepsy. Their presence may have severe implications for patients’ quality of life.

A new study indicates that infection with Helicobacter pylori might lower the risk of multiple sclerosis, at least in women. Pharmaceutical products could provide a novel means of treatment.

Orexin B protects vulnerable midbrain neurons from degeneration and preserves their function. This sleep-promoting protein could provide a new target for potential treatments.

Despite butterbur’s potential efficacy, doubts are increasing about its long-term safety given of the risk of liver damage and the lack of an actively regulated preparation.

The risk of progressive multifocal leukoencephalopathy in patients receiving Tysabri for MS is a concern about this otherwise extremely effective therapy.

HDIT/HCT could induce sustained remission and neurological improvements in patients with multiple sclerosis.

Inquiring about memory in older persons during routine clinical examination may identify persons who might be at higher risk for stroke.

This report reflects the changing nature of guidelines toward evidence-based treatment rather than expert opinion. A companion piece will help translate evidence-based guidelines to clinical practice.

Men and women smoke for different reasons and activate different parts of the brain while smoking. These findings from “dopamine movies” could have implications for Parkinson disease.

Prostaglandin may block protective microglial cells in Alzheimer disease, a study shows. This work could form the basis for future therapies.

This is a newly identified association between the conditions, and they may share a common underlying link.

By localizing the portion of the brain responsible for seizures and envisioning long-term outcomes, this imaging combination helps guide clinical decision making.

Many patients with brain tumors present with isolated headaches but no other symptoms. Use neuroimaging to help the diagnosis, or cut costs?

Transcranial magnetic stimulation is a promising, effective, well-tolerated and safe treatment option for migraine with and without aura, episodic or chronic.

Chemotherapy-induced peripheral neuropathy affects nearly half of adult cancer patients; a new review finds that there is currently no way to predict who will be affected.

This yellow CSF was drawn from an HIV-positive man who presented with status epilepticus. What is the most likely cause?

These review articles published in 2014 cover a variety of headache issues, and all are free courtesy of PubMed. Take a look.

Recovery from a paralyzed limb may be enhanced by a combination of these elements.

New research sheds light on epilepsy concerns, particularly the link between cardiac abnormalities and sudden unexpected death.

Parkinson and other neurodegenerative diseases are hard to distinguish. Surface-based MRI shows promise as a diagnostic tool.

Get to the root of the latest research findings on nervous system disorders and test your brainpower with this quick 5-question quiz.