Neurology Unwrapped: 2024’s Most Intriguing Conversations
December 27th 2024Mind Moments®, a podcast from NeurologyLive®, brings you a review of 2024, with insights from Daniel Ontaneda, MD, PhD; Ian Kremer; Andy Berkowski, MD, PhD; Sameea Husain-Wilson, DO; Jonathan Parker, MD, PhD; and Lawrence Robinson, MD. [LISTEN TIME: minutes]
Advancing the Diagnostic Criteria for Multiple Sclerosis: A New Era of Early Detection and Precision
December 24th 2024With new revisions of the MS diagnostic criteria being made, clinicians highlighted key updates and the broader implications it has for diagnosis, treatment, and healthcare practices worldwide.
Understanding the Critical and Emerging Role of Complement in Neurological Disorders
December 23rd 2024The complement system is critical in immune defense and tissue homeostasis, but its dysregulation can contribute to autoimmune neurological disorders and neurodegenerative diseases like Alzheimer, ALS, and multiple sclerosis.
PTC Formally Submits NDA for Vatiquinone as Treatment for Adults and Children With Friedreich Ataxia
December 23rd 2024Vatiquinone, a small molecule inhibitor, demonstrated its efficacy and safety across a range of age groups with Friedreich ataxia, with effects seen on disease progression and specific subscales of the mFARS.
IJMSC Insights: Ahmed Zayed Obeidat on the Intersection of Art and Medicine
December 23rd 2024IJMSC Insights offers a closer look at the latest research and the people behind it from the community of the International Journal of Multiple Sclerosis Care (IJMSC) and the Consortium of Multiple Sclerosis Centers (CMSC).
Syn-One Test Displays Significant Clinical Utility for the Diagnosis of Synucleinopathies
December 22nd 2024Since the Syn-One Test only needs a small punch skin biopsy that can be collected in an office setting, the clinical utility can be enhanced to offer more geographically convenient access for patients earlier in the disease.
Breathing Life Into ALS Care: The Vital Role of Multidisciplinary Teams
December 20th 2024Managing ALS, particularly its respiratory complications, requires a collaborative multidisciplinary team—including neurologists, pulmonologists, and respiratory therapists—working together to address the complexities of respiratory failure, the leading cause of death in these patients.
Parkinson Agent Prasinezumab Misses Primary End Point But Shows Positive Effects in Other Outcomes
December 20th 2024Although the primary goal was not met, prasinezumab demonstrated encouraging effects on secondary and exploratory measures, such as time to worsening motor function, Clinical Global Impression of Change, MDS-UPDRS motor scores.
IJMSC Insights: Blanca De Dios Perez on Employment and Multiple Sclerosis
December 19th 2024IJMSC Insights offers a closer look at the latest research and the people behind it from the community of the International Journal of Multiple Sclerosis Care (IJMSC) and the Consortium of Multiple Sclerosis Centers (CMSC).
Phase 1 Proof-of-Mechanism Study of ALS Therapy QRL-101 Begins Dosing
December 19th 2024The proof-of-mechanism study will evaluate single doses of QRL-101 in approximately 12 patients with ALS, focusing on excitability biomarkers like the strength-duration time constant (SDTC), safety, tolerability, and plasma pharmacokinetics, with topline results expected in early 2025.