The NeurologyLive® multiple sclerosis (MS) Advanced Practice Providers (APPs) clinical focus page is a concentrated place for the latest information on the care and management of patients with MS, including relapsing MS and progressive MS, as well as related and demyelinating disorders such as neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease. This page includes podcasts, videos and expert interviews, and news about the latest study and clinical trial findings, FDA actions, and clinical guideline updates.
February 3rd 2025
Deborah Benzil, MD, FAAS, vice chair of neurosurgery at Cleveland Clinic's Center for Spine Health, shared her extraordinary journey of resilience, from overcoming repeated rejections to becoming a trailblazer for women in neurosurgery, and reflects on the progress made and the challenges that remain.
Understanding Smoldering Disease in MS Beyond Focal Inflammatory Activity: Antonio Scalfari, MD, PhD
September 10th 2024The consultant neurologist at Imperial College Healthcare Trust talked about how smoldering disease in multiple sclerosis encompasses disease progression independent of relapsing activity, thus broadening the scope beyond traditional measures. [WATCH TIME: 4 minutes]
FDA Fast Tracks Autologous Treg Therapy ABA-101 for Progressive Multiple Sclerosis
August 29th 2024ABA-101 has shown promising safety and anti-inflammatory effects in animal models, and Abata Therapeutics plans to initiate a Phase 1 study in 2024 to evaluate its potential for treating progressive multiple sclerosis.
Potential of BTK Inhibitors for Primary Progressive Multiple Sclerosis: Patricia K. Coyle, MD
Published: July 23rd 2024 | Updated: June 11th 2024The professor of neurology at Stony Brook Medicine talked about the promising potential in ongoing studies assessing BTK inhibitors as treatment for primary progressive multiple sclerosis. [WATCH TIME: 3 minutes]
Optimizing Localization in Multiple Sclerosis Diagnosis: Aliza Ben-Zacharia, PhD, DNP, ANP-BC, FAAN
July 23rd 2024The assistant professor at Hunter College talked about the approach of localization to prevent misdiagnoses of multiple sclerosis and ensure patients receive appropriate treatment. [WATCH TIME: 3 minutes]
Updates in Therapeutic Development: Clinical Trial Readouts to Watch in the Second Half of 2024
July 17th 2024Take a look at some of the most-anticipated clinical trials with expected data readouts in the second half of 2024 that researchers and clinicians in neurology should keep an eye out on.
Overviewing the N-MOmentum Trial of Inebilizumab for NMOSD: Bruce Cree, MD, PhD, MAS, FAAN
June 11th 2024The clinical research director of the UCSF Multiple Sclerosis Center provided an overview of the phase 2/3 N-Momentum study assessing the efficacy of inebilizumab in patients with neuromyelitis optica spectrum disorder. [WATCH TIME: 5 minutes]
Recognizing the Clinical Features of MOGAD for Diagnosis: Eoin P. Flanagan, MB, BCh
Published: June 2nd 2024 | Updated: June 6th 2024The professor of neurology at Mayo Clinic talked about how MOG antibody-associated disease can be diagnosed through specific antibody tests, highlighting its distinct clinical and MRI features. [WATCH TIME: 4 minutes]
A Call to Action to Address Disparities in Multiple Sclerosis Care: Jaime Imitola, MD
Published: May 6th 2024 | Updated: May 6th 2024The chief of the Division of MS and Neuroimmunology at UConn Health talked about the challenges with access to care in multiple sclerosis, particularly for marginalized communities, despite significant progress made in the field over the past decades. [WATCH TIME: 4 minutes]
Pregnancy Outcomes of Maternal Exposure to Ocrelizumab: Riley Bove, MD
April 16th 2024The associate professor of neurology at University of California, San Francisco talked about findings from an analysis that assessed the safety of ocrelizumab when administered close to pregnancy. [WATCH TIME: 5 minutes]
New Insights into BTK Inhibitors and MRI Techniques for Smoldering MS: Thomas F. Scott, MD
April 14th 2024The director of the Allegheny Multiple Sclerosis Treatment Center at Allegheny General Hospital discussed exploring the potential role of BTK inhibitors and advanced MRI techniques to address smoldering multiple sclerosis. [WATCH TIME: 10 minutes]
Benefits of Telemedicine and Access to Treatments for Multiple Sclerosis: Jai Perumal, MD
April 2nd 2024The associate professor of clinical neurology at Weill Cornell Medicine discussed the progress made in multiple sclerosis in terms of expanding access to therapies and the challenges that persist for progressive forms of the disease in the field. [WATCH TIME: 10 minutes]
Analyzing Cognitive Profiles in Multiple Sclerosis and Alzheimer Disease: Le Hua, MD
March 27th 2024The director of the Multiple Sclerosis Program at the Cleveland Clinic’s Lou Ruvo Center for Brain Health discussed findings from a study that compared cognitive profiles between patients with multiple sclerosis and Alzheimer disease. [WATCH TIME: 5 minutes]
The Evolving Landscape of Treatments for Multiple Sclerosis in 2024: Enrique Alvarez, MD, PhD
February 14th 2024The associate professor of neurology at the University of Colorado School of Medicine talked about promising developments in multiple sclerosis treatment strategies for 2024. [WATCH TIME: 6 minutes]