Durability and Next Steps in Advancing ARCUS Gene Editing Platform in DMD: Cassandra Gorsuch, PhD
April 26th 2025The chief scientific officer at Precision Biosciences provided clinical insights on the durable potential of ARCUS gene editing and the company’s next steps toward in-human trials for Duchenne muscular dystrophy. [WATCH TIME: 4 minutes]
Overview of Status Epilepticus and Prolonged Seizures in Epilepsy
April 25th 2025A panelist discusses how early recognition and intervention in prolonged seizures and status epilepticus are essential to prevent neuronal injury, reduce long-term complications, and improve overall quality of life for patients.
Treatment Options for Advanced Parkinson Disease
April 25th 2025Panelists discuss how alternative formulations and administration routes like Levodopa/carbidopa intestinal gel and deep brain stimulation have impacted advanced Parkinson disease management, including which patient populations benefit most and when these options are recommended.
CIDP Treatment Options and Treatment Selection Criteria
April 24th 2025Panelists discuss how selecting the appropriate treatment for chronic inflammatory demyelinating polyneuropathy (CIDP) involves considering disease characteristics, patient preferences, and treatment response, with options ranging from intravenous immunoglobulin (IVIg) to emerging therapies based on individual needs and safety considerations.
Patient Perspectives and Expert Tips on Managing CSAI Challenges in PD
April 24th 2025Pagan shared insights from InfusON patient interviews on the challenges and benefits of initiating CSAI therapy and discussed how expert roundtable recommendations can guide neurologists in managing skin nodules associated with treatment.
Impact of CIDP on Quality of Life and Importance of Early Intervention
April 24th 2025Panelists discuss how chronic inflammatory demyelinating polyneuropathy (CIDP) can significantly impair quality of life for both patients and caregivers, emphasizing that early recognition and timely treatment are essential to prevent irreversible damage and improve long-term outcomes.
Comparable Evidence of Telehealth Benefits vs In-Person Care for Pediatrics: Gogi Kumar, MD
April 23rd 2025The division chief of child neurology at Dayton Children’s Hospital discussed findings from a study comparing patient satisfaction scores between telehealth and in-person visits in pediatric epilepsy care. [WATCH TIME: 4 minutes]
Adjusting and Changing Treatment Regimens in Parkinson Disease
Panelists discuss how treatment changes in Parkinson disease are necessitated by disease progression, diminishing medication effectiveness, and emerging motor complications, examining a physician’s systematic approach to treatment adjustments and the range of available options for managing off fluctuations.
Off Fluctuations in Parkinson Disease
Panelists discuss how off fluctuations in Parkinson disease become increasingly prevalent as the disease progresses, significantly impacting patient quality of life through reduced mobility, independence, and overall well-being.
Unveiling ARCUS Gene Editing Platform and Its Potential in DMD: Cassandra Gorsuch, PhD
April 23rd 2025The chief scientific officer at Precision Biosciences provided clinical commentary on ARCUS gene editing platform and its potential application in Duchenne muscular dystrophy through a durable, AAV-delivered therapeutic strategy. [WATCH TIME: 4 minutes]
Improving Access to Surgical Evaluation in Drug-Resistant Epilepsy: Satyanarayana Gedela, MD
April 22nd 2025The division chief of neurology at Nemours Children’s Hospital spoke on the need for timely referrals to epilepsy centers for patients with drug-resistant epilepsy. [WATCH TIME: 5 minutes]
Assessing Clinical Relevancy of Visual Biomarkers in Alzheimer Disease: Alfredo A. Sadun, MD, PhD
April 22nd 2025The chief of ophthalmology at the Doheny Eye Institute discussed decades of research uncovering how Alzheimer can impact visual function and how retinal imaging may advance diagnosis. [WATCH TIME: 13 minutes]
Rethinking Alzheimer Diagnosis and Disease Staging: Clifford Jack, MD
April 21st 2025The neuroradiologist at Mayo Clinic discussed the clinical and conceptual differences between Alzheimer disease diagnostic frameworks and how clinicians should prepare for a shifting treatment landscape. [WATCH TIME: 4 minutes]
Excitement Around New Therapeutics in Parkinson Disease
April 21st 2025Pagan discusses the excitement surrounding new therapeutics in neurodegenerative diseases and how advances in protein clearance and inflammation reduction could lead to disease-modifying treatments for conditions like Parkinson disease.
Real-World Impact of CSAI on Motor Fluctuations in PD
April 21st 2025Fernando L. Pagan, MD, discussed how continuous subcutaneous apomorphine infusion impacts long-term motor fluctuations in Parkinson disease, highlighting InfusON extension study findings on uninterrupted "good ON" time and reduced "OFF" periods as evidence of its real-world efficacy.
Evaluating Safety and Early Outcomes of Lecanemab Treatment for Alzheimer Disease: Philip Kuball, MD
April 18th 2025The resident in the Department of Neurology at NYU Langone Health discussed the preliminary findings of a 9-month study on lecanemab recently presented at the 2025 AAN Annual Meeting. [WATCH TIME: 2 minutes]
Celebrating Innovation in MS Research With the John Dystel Prize: Bruce Bebo, PhD
April 17th 2025The executive vice president of research at the National MS Society talked about how the award continues to honor transformative multiple sclerosis research and inspire the next generation of investigators. [WATCH TIME: 5 minutes]
Diagnosis and Treatment of Alzheimer’s Disease
April 17th 2025Panelists discuss how cognitive testing tools, functional assessments, and biomarker integration guide Alzheimer’s disease diagnosis and staging, while early identification enables timely access to disease-modifying therapies, care coordination, and improved long-term outcomes.