Videos

Severe Preeclampsia Linked With Neuroinflammation, Neurofilament Light Associated With Memory Function, Discrimination Effects on Cognition

The medical director of the North Texas Institute of Neurology and Headache offered an overview of the State of the Science Summit that was held on July 21, 2022, with a variety of expert clinicians in MS care. [WATCH TIME: 3 minutes]

NeurologyLive® Staff

August 6th 2022

Advice for Managing Dravet Syndrome and LGS

Neurology News Network for the week ending August 6, 2022. [WATCH TIME: 4 minutes]

Joseph Sullivan, MD;Kelly Knupp, MD;Mary Anne Meskis;Tracy Dixon-Salazar, PhD

Resources for Dravet Syndrome and LGS

Mary Anne Meskis; Tracy Dixon-Salazar, PhD; Kelly Knupp, MD; and Joseph E. Sullivan, MD, provide advice for physicians treating patients with Dravet syndrome or LGS.

Joseph Sullivan, MD;Kelly Knupp, MD;Mary Anne Meskis;Tracy Dixon-Salazar, PhD

Challenges in Treatment Selection in LGS

Kelly Knupp, MD; Mary Anne Meskis; and Tracy Dixon-Salazar, PhD, share education around patient advocacy and support groups as well as other resources for patients with Dravet syndrome or LGS.

Joseph Sullivan, MD;Kelly Knupp, MD;Mary Anne Meskis;Tracy Dixon-Salazar, PhD

The Mount Sinai Perspective on the State of MS Care: Stephen Krieger, MD

Tracy Dixon-Salazar, PhD, leads a discussion on challenges of treating LGS and real-world implications from clinical trial data on newer medications.

Stephen Krieger, MD

Understanding the Neuropathological Link Between Preeclampsia and Neuroinflammation, Neurovascular Damage: Vesna Garovic, MD, PhD

The neurologist at the Corinne Goldsmith Dickinson Center for MS offered an overview of the State of the Science Summit that was held on June 30, 2022, with a variety of expert clinicians from Mount Sinai. [WATCH TIME: 7 minutes]

Vesna Garovic, MD, PhD

Immunogenicity and Disease-Modifying Therapies

The nephrologist at Mayo Clinic provided insight on new data showing elevated extracellular vesicles of neurovascular origin in women with a history of severe preeclampsia years after pregnancy. [WATCH TIME: 4 minutes]

Jeffrey Dunn, MD;Regina Berkovich, MD, PhD

Considerations for Infection Risk in Patients With MS

Jeffrey Dunn, MD, and Regina Berkovich, MD, PhD, provide an overview of the impact vaccinations and immunization may have on multiple sclerosis therapies, highlighting the ability of S1P treatments to remain effective.

Jeffrey Dunn, MD;Regina Berkovich, MD, PhD

Novel and Emerging Targets in Multiple Sclerosis

Regina Berkovich, MD, PhD, provides insight on the considerations and patient awareness of the risk of infections with disease-modifying therapies in patients with multiple sclerosis.

Scott Newsome, DO, MSCS, FAAN;Lawrence Steinman, MD;Ahmed Obeidat, MD, PhD;Amit Bar-Or, MD, FRCPC;Bridget A. Bagert, MD, MPH

Moving From the Bench to the Bedside in MS Management

Experts in neurology share their hopes for the future of multiple sclerosis treatment and discuss unmet needs and novel targets.

Scott Newsome, DO, MSCS, FAAN;Lawrence Steinman, MD;Ahmed Obeidat, MD, PhD;Amit Bar-Or, MD, FRCPC;Bridget A. Bagert, MD, MPH

Hidden Symptoms of Multiple Sclerosis

Amit Bar-Or, MD, FRCPC, and Bridget A. Bagert, MD, share their opinions on how to move investigative treatments for multiple sclerosis off the laboratory bench and into clinical practice.

Scott Newsome, DO, MSCS, FAAN;Lawrence Steinman, MD;Ahmed Obeidat, MD, PhD;Amit Bar-Or, MD, FRCPC;Bridget A. Bagert, MD, MPH

Monitoring and Follow-Up of Acute Migraine

Doctors in neurology comment on the hidden symptoms of multiple sclerosis and debate whether they should be treatment targets.

Kita Williams, MD

Advice for Clinical Management of Multiple Sclerosis

A migraine specialist discusses monitoring of patients with acute migraine.

Darin Okuda, MD

Role of Midlevel Staff in Migraine Management

Dr Okuda shares his thoughts on the importance of patient dialogue in successful management of multiple sclerosis.

Kita Williams, MD

Long-Term Outcomes With Ozanimod Based on Number of MS Relapses

Dr Williams talks about the role NP/PA play in treating patients with migraines.

Darin Okuda, MD

Managing Relapses in Patients With Multiple Sclerosis

A multiple sclerosis expert, Dr Darin Okuda reviews long-term outcomes with ozanimod in DAYBREAK trial based on the number of relapses that was presented at EAN 2022.

Darin Okuda, MD

Gaps in Care in Myasthenia Gravis and Take-Home Points

Dr Darin Okuda discusses strategies for treatment selection and management of relapses in multiple sclerosis.

Ericka Wong, MD

Zilucoplan and Other Pipeline Agents in the Treatment of Myasthenia Gravis

Ericka Wong, MD, comments on gaps in care in myasthenia gravis and provides take-home messages for physicians treating patients with this condition.

Ericka Wong, MD

Using Nonamnestic Cognitive Symptoms to Predict Trajectories of Neurodegenerative Disorders: Jagan A. Pillai, MD, PhD

An expert neurologist discusses zilucoplan and other pipeline agents in the treatment of myasthenia gravis.

Jagan A. Pillai, MD, PhD

Formulating the Right Combination of Acoustic Metrics to Quantify Cognitive Impairment: Alvaro Pascual-Leone, MD, PhD

The neurologist at Cleveland Clinic’s Lou Ruvo Center for Brain Health detailed new findings on whether initial cognitive symptoms have similar rates of functional decline across a handful of neurodegenerative disorders. [WATCH TIME: 3 minutes]

Alvaro Pascual-Leone, MD, PhD

Using Neurofilaments as a Biomarker in MS

The chief medical officer and cofounder of Linus Health provided background on the reasoning for the measures used in a new machine learning algorithm that classifies cognitive status. [WATCH TIME: 3 minutes]

Stephen Krieger, MD;Heidi Crayton, MD;Jacqueline Nicholas, MD, MPH;Flavia Nelson, MD

Safety Considerations and Monitoring for S1P Modulators in MS

Dr Jacqueline Nicholas hypothesizes about the utility of neurofilaments as a biomarker of disease severity in patients with multiple sclerosis.

Stephen Krieger, MD;Heidi Crayton, MD;Jacqueline Nicholas, MD, MPH;Flavia Nelson, MD

History and Future Outlook of V236E and R251G Missense Variants in Alzheimer disease: Yann Le Guen, PhD

Heidi Crayton, MD, and Jacqueline Nicholas, MD, review the importance of long-term safety data in the management of patients with multiple sclerosis, and Flavia Nelson, MD, discusses her approach to counseling patients on the safety considerations regarding new S1P modulating agents.

Yann Le Guen, PhD

Using Machine Learning, Speech Production to Quantify Mild Cognitive Impairment: Alvaro Pascual-Leone, MD, PhD

The assistant director of computational biology at Stanford University discussed the knowns and unknowns of 2 rare missense variants and their associations with decreased Alzheimer disease risk. [WATCH TIME: 4 minutes]

Alvaro Pascual-Leone, MD, PhD

August 2nd 2022

AUPN Leadership Minute Episode 24: How Much Is a Neurologist Worth: Factoring the Downstream

The medical director of the Deanna and Sidney Wolk Center for Memory Health provided background on his new study using multimodal digital biomarkers to classify patients with mild cognitive impairment. [WATCH TIME: 5 minutes]

Alissa Willis, MD;Joseph R. Berger, MD

August 1st 2022

Complexities With SMN2 Copies in Spinal Muscular Atrophy: Basil Darras, MD

Episode 24 of the AUPN Leadership Minute features Alissa Willis, MD, of University of Mississippi Medical Center; and Joseph R. Berger, MD, of the University of Pennsylvania. [WATCH TIME: 7 minutes]

Basil Darras, MD

August 1st 2022

Examining the Association of APOE Missense Variants and the Risk of Alzheimer Disease: Yann Le Guen, PhD

The associate neurologist-in-chief at Boston Children’s Hospital discussed the 4-copy conundrum and whether treatment decisions differ based on SMN2 copies for patients with spinal muscular atrophy. [WATCH TIME: 2 minutes]

Yann Le Guen, PhD

July 31st 2022