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Epilepsy in Pediatric Population: Prevalence, Pathophysiology, and Disease Heterogeneity

Key Takeaways

  • Pediatric epilepsy affects 0.5-1% of children, with increased prevalence in those with developmental disabilities.
  • Abnormal electrical brain activity, genetic mutations, structural abnormalities, and metabolic disorders contribute to epilepsy pathophysiology.
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John Michael Schreiber, MD, provides an overview of epilepsy in infant and pediatric patients, including its prevalence, and describes the pathophysiology of infantile and pediatric epilepsy, highlighting how the disease’s heterogeneity affects diagnosis.

  1. Please provide an overview of epilepsy in infant and pediatric patients.
    • What is the prevalence of epilepsy in pediatric patients?
  2. Please describe the pathophysiology of infantile and pediatric epilepsy.
  • How does the heterogeneity of the disease affect diagnosis?
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