Episode 83: The ARISE Study and Using DMTs in RIS

Darin Okuda, MD, FAAN, FANA

Episode 83 of the NeurologyLive^® Mind Moments^® podcast is now live! Scroll down to listen or click here to subscribe on your favorite streaming service.

The Mind Moments^® podcast features exclusive interviews with leaders in the field discussing the latest research and disease management strategies across the breadth of neurology, including epilepsy, multiple sclerosis, Parkinson disease, dementia, sleep disorders, and more.

Episode 83, "The ARISE Study and Using DMTs in RIS," features an exclusive interview with Darin Okuda, MD, FAAN, FANA, director of Neuroinnovation and Multiple Sclerosis & Neuroimmunology Imaging Program at UT Southwestern Medical Center. He spoke about the phase 2 ARISE study assessing dimethyl fumarate (Tecfidera; Biogen) in patients with radiologically isolated syndrome, the significance of the findings, next steps in validating this therapy, and more.

This episode is brought to you by Medical World News, a streaming channel from MJH Life Sciences^®. Check out new content and shows every day, only at medicalworldnews.com

The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:

• CNM-Au8 Shows Positive Findings on MS-Related Biomarkers of Whole Brain, White Matter
• Aducanumab’s Label Updated to Include Risks on Brain Bleeding
• Primary Care Physicians Show Greater Confidence in Diagnosing Alzheimer Disease Through DISCERN Skin Test
• FDA Approves Extended-Release Deutetrabenazine for Huntington Disease Chorea, Tardive Dyskinesia

EPISODE BREAKDOWN

• 1:20 – Overview of ARISE and conduct of study
• 4:20 – Potential subgroup responders to dimethyl fumarate
• 8:10 – Efforts to improve the detection of radiologically isolated syndrome
• 10:05 – Neurology News Minute
• 11:55 – Next steps of research following ARISE
• 16:50 – Closing thoughts on significance of the study

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REFERENCE
Okuda DT, Kantarci O, Lebrun-Frenay C, et al. Dimethyl fumarate delays multiple sclerosis radiologically isolated syndrome. Ann Neurol. 2023;93(3):604-614. doi:10.1002/ana.26555