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Five recent studies offer new insights on migraine headaches-- its pathophysiologic underpinnings and various modes of therapy.The five slides that follow summarize the key points of those studies and include links to more details. Among the findings:. Evidence-based recommendations for treatment for acute migraine relief in the ED have emerged.. 2 studies report a migraine preventive effect from an entirely novel mechanism--calcitonin gene-related peptide blockade.. There's a link between mid-life migraine and later life Parkinson Disease and parkinsonian symptoms.. The menopausal transition is associated with an increased frequency of migraines.. The newly FDA-approved Cefaly device can be considered a low risk preventative option for patients with episodic migraineÂ