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In this segment, Pagan talked about how the field of neurology has changed in the last decade and shared where he sees it moving forward as well.  

Reflecting on the Rapid Evolution of Neurology 

Articles

Roche has updated its phase 3 GENERATION HD2 trial to continue testing only the higher 100 mg dose of tominersen, following interim data favoring its potential clinical benefit in Huntington disease.

GENERATION HD2 Trial of Huntington Agent Tominersen Amended to Include Only Higher Dose

Pagan shared insights from InfusON patient interviews on the challenges and benefits of initiating CSAI therapy and discussed how expert roundtable recommendations can guide neurologists in managing skin nodules associated with treatment. 

Patient Perspectives and Expert Tips on Managing CSAI Challenges in PD 

The switch from 1 anti-CGRP monoclonal antibody to another led to a significant reduction in monthly headache days, regardless of target mechanism, dose history, or time between treatments.

Switching Between Anti-CGRP Monoclonal Antibodies Reduces Headache Days in Non-Responders

Division Chief of Neurology, Dayton Children's Hospital

The division chief of child neurology at Dayton Children’s Hospital discussed findings from a study comparing patient satisfaction scores between telehealth and in-person visits in pediatric epilepsy care. [WATCH TIME: 4 minutes]

Comparable Evidence of Telehealth Benefits vs In-Person Care for Pediatrics: Gogi Kumar, MD

Interim chief executive officer of the Consortium of Multiple Sclerosis Centers.

IJMSC Insights offers a closer look at the latest research and the people behind it from the community of the International Journal of Multiple Sclerosis Care (IJMSC) and the Consortium of Multiple Sclerosis Centers (CMSC).

IJMSC Insights: Kathleen Costello, Interim CEO of CMSC

The neuroradiologist at Mayo Clinic discussed the clinical and conceptual differences between Alzheimer disease diagnostic frameworks and how clinicians should prepare for a shifting treatment landscape. [WATCH TIME: 4 minutes]

Rethinking Alzheimer Diagnosis and Disease Staging: Clifford Jack, MD

Resident in the Department of Neurology at NYU Langone Health.

The resident in the Department of Neurology at NYU Langone Health discussed the preliminary findings of a 9-month study on lecanemab recently presented at the 2025 AAN Annual Meeting. [WATCH TIME: 2 minutes]

Evaluating Safety and Early Outcomes of Lecanemab Treatment for Alzheimer Disease: Philip Kuball, MD

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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Pain related to more severe motor symptoms, phosphodiesterase 10A loss seen early, novel therapy shows promise, and other recent findings are summarized here.

Clinical

SUP-22-NRD0184 - /clinical/movement-disorders

Parkinson Disease: 5 Updates