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Newborn Screening Awareness Month: Understanding the Impact of Newborn Screening for SMAAdvocacy organization Cure SMA provides insight on the importance of continuing to push for standardized newborn screening and how it can positively impact outcomes in SMA.
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The Significance of Gene Therapy in Neuromuscular Medicine at the 2025 MDA Conference: Paul Melmeyer, MPPPrior to the 2025 MDA Conference, the vice president of Public Policy & Advocacy at the Muscular Dystrophy Association talked about the increasing interest in gene therapy in the field of neuromuscular diseases.
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Sudden Unexpected Death in Epilepsy Linked With Sleep: Sanjeev Kothare, MDThe division director of pediatric neurology, and director of the pediatric sleep program at Cohen, Children's Medical Center, Northwell Health, spoke about sudden unexpected death in epilepsy and sleep at the 2022 AES Conference. [WATCH TIME: 3 minutes]
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Reactions to FDA Advisory Panel Decision on AMX0035: Justin Klee; Josh Cohen, BScThe co-CEOs and co-founders of Amylyx Pharmaceuticals discussed their immediate thoughts to the recent FDA AdComm meeting, which voted against evidence of efficacy for AMX0035 in ALS. [WATCH TIME: 3 minutes]
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Reasons to Attend the 2023 Advanced Therapeutics in Movement & Related Disorders Congress: Fernando Pagan, MD; Yasar Torres-Yaghi, MDThe course directors of the 2023 ATRMD Congress provided an overview of the upcoming meeting, and the educational benefits clinicians can gain from attending. [WATCH TIME: 6 minutes]
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Understanding the Microglial Immunologic Sex Differences in Alzheimer Disease: Feixiong Cheng, PhDThe assistant professor at Cleveland Clinic discussed findings from a recently published study that provided insights on the understanding of the molecular basis for female predominance in Alzheimer disease. [WATCH TIME: 3 minutes]
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AUPN Leading Edge Episode 4: How Much Is a Neurologist Worth? Factoring the DownstreamAUPN Leading Edge Episode 4 features Rohit Das, MD, and Joseph R. Berger, MD, who discuss how neurologists are undervalued in academic and non-academic settings when their compensation is predicated on RVUs alone. [LISTEN TIME: 26 minutes]
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Virendra Mishra, PhD: Previous Data on Parkinson Disease DementiaThe Cleveland Clinic researcher discussed the unknowns about Parkinson disease dementia and what has been previously observed in clinical studies.
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Building a Greater Knowledge Profile of Sodium Oxybate Treatment for Narcolepsy: Phil Jochelson, MDThe therapeutic head for Clinical Development Neuroscience at Jazz Pharmaceuticals discussed how sodium oxybate has evolved over the years and the educational aspects of cardiovascular implications patients and clinicians should be aware of. [WATCH TIME: 3 minutes]
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Identifying Impactful Biomarkers of Alzheimer Disease: Sudhir Sivakumaran, PhD; Klaus Romero, MD, MS, FCPThe duo from the Critical Path Institute detailed the thought process behind evaluating the importance of specific biomarkers and their relation to disability progression in Alzheimer disease.
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Emerging Therapies in Movement Disorders and Chronic Care Management for Parkinson Disease: Safia Abdillahi, ACNP-BC, DNPThe nurse practitioner in the movement disorder division at Georgetown University Hospital discussed differences in available therapies for movement disorders versus multiple sclerosis and using a chronic care management model in Parkinson disease. [WATCH TIME: 5 minutes]
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Advancements in Minimally Invasive Epilepsy Surgery Techniques: Hai Sun, MD, PhDThe associate professor of neurosurgery at Robert Wood Johnson Medical School talked about minimally invasive techniques and neurostimulation strategies to make epilepsy surgery safer and more effective. [WATCH TIME: 7 minutes]
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Clinical Pearls for Management of Generalized Myasthenia GravisPanelists discuss how a multidisciplinary approach involving various specialists is crucial in managing generalized myasthenia gravis (gMG), offering final insights and recommendations for health care professionals treating gMG patients.
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Reframing the Communication of Lifestyle Changes for Migraine Management: Elizabeth Seng, PhDThe associate professor at Yeshiva University and Albert Einstein College of Medicine explored the challenge of discussing lifestyle changes for patients with migraine, noting that lifestyle modifications can be a valuable addition to migraine treatment. [WATCH TIME: 3 minutes]
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Understanding Race-Gender Associations in Insomnia Patterns and Late-Life Memory Trajectories: Afsara ZaheedThe graduate student at the University of Michigan provided insight on her study examining longitudinal patterns of difficulty initiating sleep and their associations with subsequent memory trajectories among different races and genders. [WATCH TIME: 3 minutes]
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Burnout Among Healthcare Providers Affects Worker Quality of Life and Reduces Quality of Patient CareMany programs and activities at the 2023 CMSC Annual Meeting focused on burnout prevention and supporting the current and future MS care workforce.
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Assessing Phase 2 Data on Bepranemab’s Effect on Tau Accumulation and Cognitive Function: Matthew Barton, PhDThe head of global clinical development for immunology/bone at talked about findings presented at CTAD 2024 from the phase 2 trial assessing bepranemab in Alzheimer disease. [WATCH TIME: 3 minutes]
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Unmet Needs and Advice for the Management of OFF Episodes in Parkinson DiseaseExpert neurologists provide insight on unmet needs, challenges to improve access to care, and highlight clinical pearls for the management of OFF episodes in Parkinson disease.
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Mechanism Behind Ulixacaltamide to Treat Essential Tremor: Marcio SouzaThe president and chief executive officer at Praxis Precision Medicine provided clinical insight on the promising build of ulixacaltamide, an investigational, selective agent in development for essential tremor. [WATCH TIME: 3 minutes]
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Differences Between Antiamyloid Therapies Lecanemab and Donanemab: Martin Sadowski, MD, PhDThe professor of neurology, psychiatry, and pharmacology at the NYU Grossman School of Medicine commented on the differences in mechanisms and clinical trial data between lecanemab and donanemab. [WATCH TIME: 5 minutes]
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Clinical Trial Experiences Managing Adverse Events in Gene Therapy for DMD: Natalie L. Goedeker, CPNPAt the 2023 MDA Conference, a neurology nurse practitioner in the Neuromuscular Division at Washington University in St. Louis talked about adverse event management of gene therapies in Duchenne muscular dystrophy. [WATCH TIME: 2 minutes]
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Expanding Research on MS Diagnosis Disclosure and Long-Term Impacts: Anne Kever, PhDThe postdoctoral researcher at Columbia University discussed the long-term plans to gain a better understanding of MS diagnosis disclosure and how it can impact other qualities of life.
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The Classification, Management, and Future Directions of Neonatal Seizures: Elissa Yozawitz, MDThe associate professor of neurology at Albert Einstein College of Medicine talked about a review on neonatal seizures recently published in the New England Journal of Medicine. [WATCH TIME: 5 minutes]
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Applying the Innovation Biodesign Framework to Promote Equity and Green Activity in Dementia CareLassell et al present a use case demonstrating the process of moving an unmet need to the “solution space” of the Innovation Biodesign Framework for addressing a healthcare challenge in a specific at-risk population: Alzheimer disease and AD-related dementias.
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Advice for Managing MSJoseph R. Berger, MD, and Fred D. Lublin, MD, offer advice to community physicians and neurologists in managing patients with multiple sclerosis.
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A New Approach to Communicating Hydrocephalus: An Overdue OpportunityA pair of cerebrovascular and neurosurgery experts discuss a novel approach to communicating hydrocephalus with an arachnoid granulation using a miniature implant, delivered via a percutaneous endovascular catheter.
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Evolving Role of Deep Brain Stimulation for Parkinson Disease, Essential Tremor: Julie Pilitsis, MD, PhD, MBAThe neurosurgeon at Marcus Neuroscience Institute, Baptist Health, provided perspective on the advances of DBS and other invasive procedures for patients with degenerative disorders. [WATCH TIME: 4 minutes]
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Using a Blood Collection Device to Advance Genetic Research in Parkinson Disease: James Beck, PhD & Ben Casavant, PhDThe chief scientific officer of the Parkinson’s Foundation and chief executive officer of Tasso discussed their company partnership to expand and accelerate genetic research in Parkinson Disease. [WATCH TIME: 6 minutes]
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Transformation of Rett Syndrome Research With the Emergence of Adult Data: Walter E. Kaufmann, MDThe adjunct professor of human genetics at Emory University School of Medicine discussed previous research on Rett syndrome that initially provided crucial insight on the neuromuscular condition in adult populations. [WATCH TIME: 2 minutes]
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Understanding Differences in B-Cell Depleting Medications for MS: Kristin Galetta, MD, MSEdThe professor of neurology at Brigham and Women’s Hospital discussed her presentation on B-cell depleting therapies such as ocrelizumab and ofatumumab for the treatment of multiple sclerosis. [WATCH TIME: 2 minutes]
