Headache and Migraine

A new class of injectable monoclonal antibodies directed against calcitonin gene related peptide (CGRP) or its receptor may offer hope to migraineurs who have not found effective prophylactic therapy.

The calcitonin gene-related peptide inhibitor lowered monthly migraine days by ≥50% in 30.3% of patients compared to 13.7% on placebo.

Neurologists may be the first or only clinicians to recognize the 5 potentially dangerous neuro-ophthalmologic conditions described in this article.

Three cases. Three questions. Your diagnosis.

A study undertaken to evaluate the efficacy and tolerability of single pulse transcranial magnetic stimulation (sTMS) for the preventive treatment of migraine has led to an FDA extended indication.

Women who have migraines with aura are at increased risk of stroke. Now, a new systematic review suggests that use of combined hormonal contraceptives by these patients raises their stroke risk over and above the already increased risk.

A 5-year study assessed the association between dry eye and comorbid pain conditions in thousands of veterans and here's what they found.

With a plethora of issues currently being debated in the field of sports neurology, Dr Seifert explores the top 5.

Migraine is not characterized by neuronal degeneration, but it has been a target of stem cell therapy in a few small investigational studies--and has shown early promise.

Which medication should be avoided when your patient has an acute migraine? Which drugs should you prescribe for menstrual-associated migraine prevention? Take the quiz and learn more.

Do individuals hospitalized with head injury have new headaches or exacerbations of pre-existing headaches more often than others?

A study suggests an increase in the risk for pseudotumor cerebri syndrome with current users of fluoroquinolones. When is medical attention warranted? 

In this 6-minute video presentation, Dr. Andrew Wilner describes the epidemiology and pathophysiology of carbon monoxide poisoning and reviews the implications of a recently published observational study.

There is a surprisingly low association between airplane headaches and other types of headaches. So what are the characteristics and how are they treated?

Is there a treatment for this?

Test your skills on aspirin vs placebo; the association between trauma and headache; global burden of headache in children and adolescents, and more.

Teens survivors of terror attacks like mass shootings are 3 to 4 times more likely to suffer from frequent migraines than those who have not endured such experiences.

What are the symptoms of cluster headache? Which treatments have proven to be beneficial in relieving the pain of temporomandibular joint disorder? Those questions and more in this quiz.

What are the direct costs and indirect costs of cluster headache in the US? Here's what the first study of this issue found.

The FDA has granted a priority review designation to fremanezumab for the prevention of migraines.

The FDA has accepted a biologics license application for galcanezumab as a prophylactic treatment for migraines.

A summary of current treatment guidelines, application, and emerging developments in the area of spontaneous nontraumatic ICH.

A 71-year-old woman presented to the emergency department with subacute headaches and altered behavior that was initially attributed to emotional distress. What did the tests show?

Can treatment of subclinical hypothyroidism help diminish frequency and severity of migraines? This study suggests that levothyroxine can do both.

Migraine-especially migraine with aura-is a CV risk factor, which makes the prescription of ergots or triptans potentially problematic. What’s the best approach?

A new study makes the case for alternatives to opioids in the treatment of migraine.

An emphasis on importance of taking a detailed history and careful neurologic examination focused on the vestibular system.

The authors distinguish between the clinical entities of meningitis, encephalitis, and encephalopathy.