Latest Conference Coverage

AMX0035 Meets Primary Safety and Tolerability End Point in Alzheimer Disease

A higher incidence of gastrointestinal events was observed in the treatment group compared with placebo, similar to what was seen in clinical trials of AMX0035 in amyotrophic lateral sclerosis.

Therapeutic Approaches to Fatigue in Multiple Sclerosis: Anna Kratz, PhD

Discussing cognitive behavioral therapy for patients with MS, the associate professor of Physical Medicine and Rehabilitation and research nonclinical psychologist at the University of Michigan Medicine mentioned different therapeutic options that can benefit this patient population. [WATCH TIME: 3 minutes]

Anna Kratz, PhD, on Managing MS Fatigue in a Multifaceted Way

Anna Kratz, PhD, associate professor of Physical Medicine & Rehabilitation, University of Michigan Medicine, spoke to the benefits of a multifaceted approach to managing fatigue for patients with multiple sclerosis.

Strategies, Tools for Treating Fatigue in Multiple Sclerosis: Anna Kratz, PhD

The associate professor of Physical Medicine & Rehabilitation and research nonclinical psychologist at the University of Michigan Medicine discussed challenges when addressing fatigue, as well as the need to integrate digital tools for patients with MS. [WATCH TIME: 4 minutes]

Masupirdine Shows Beneficial Effect in Alzheimer Disease Psychosis

Over 26 weeks of treatment, masupirdine demonstrated a sustained and durable effect on outcomes such as cognition and dementia-related psychosis.

A Multidisciplinary Approach to Fatigue in Multiple Sclerosis: Anna Kratz, PhD

The associate professor of Physical Medicine & Rehabilitation and nonclinical research psychologist at University of Michigan Medicine discussed the complexities of fatigue as a symptom following her presentation at CMCS 2021.

Low-Dose Whole Brain Radiation Therapy Elicits Positive Results in Early Alzheimer Disease Dementia

A presentation at CTAD 2021 included data from 5 patients enrolled in a phase 2a trial to evaluate neurocognitive, imaging, and safety outcomes of the therapeutic approach in early AD dementia.

Patients With Dementia Willing to Restart Research Participation Interrupted by COVID-19

Findings presented at CTAD 2021 included data from surveyed participants with dementia and healthy volunteers about starting in-person or remote research.

Evaluating Ocrelizumab in the CHIMES Trial: Mitzi Joi Williams, MD

The founder and CEO of Joi Wellness Group Multiple Sclerosis Center described motivations behind the evaluation of ocrelizumab (Ocrevus; Genentech) in minority populations with multiple sclerosis.

National Alzheimer Disease Registry Announced to Collect Clinical Practice Data

The new registry will collect routine clinical practice data from the care of patients with Alzheimer disease who are taking an FDA-approved disease-modifying therapy.

Autologous Adipose Stem Cells Are Safe in Alzheimer Disease, Slightly Improve Cognitive Function

Despite the cohort only consisting of 3 patients with Alzheimer disease, autologous cellular therapy data highlighted the potential of the treatment’s results on cognitive assessments such as Montreal Cognitive Assessment.

Correlation Between Plasma Tau Reduction, Cognitive Function Linked to Aducanumab Treatment

The data, which suggest that a lessened decline in cognition and function was correlated with a reduction in plasma p-tau181 levels in those with Alzheimer disease treated with aducanumab (Aduhelm; Biogen), were presented at CTAD 2021.

Topline Data From LAURIET Study in Alzheimer Disease Confirm Prior Findings

Study of semorinemab in a larger mITT population confirmed statistically significant reduction in rate of cognitive decline in patients with Alzheimer disease, compared with placebo, but failed to achieve other end points.

Designing an MS Clinical Trial Focused on Minority Populations: Mitzi Joi Williams, MD

Outlining the development of the CHIMES trial in multiple sclerosis, the founder and CEO of Joi Life Wellness Group Multiple Sclerosis Center spoke on tactics to get underrepresented populations involved. [WATCH TIME: 2 minutes]

Developing the CHIMES Trial for Minority Patients With MS: Mitzi Joi Williams, MD

The founder and CEO of Joi Life Wellness Group Multiple Sclerosis Center outlined the motivations behind the trial, as well as potential reasons for underrepresentation. [WATCH TIME: 2 minutes]

Takeaways for MS Clinicians on COVID-19 Vaccination: Amit Bar-OR, MD, FRCPC, FAAN, FANA

The chief of the Multiple Sclerosis Division, Perelman School of Medicine at the University of Pennsylvania emphasized current recommendations, which suggest patients with MS get vaccinated for COVID-19. [WATCH TIME: 3 minutes]

Greatest Recent Advancements in MS, Looking Toward the Future: Ilya Kister, MD

The professor of neurology at the NYU Grossman School of Medicine provided his thoughts on the most notable strides within the multiple sclerosis field in the past year. [WATCH TIME: 3 minutes]

Quality of Life Improvements in MS Following Wellness Program: Brian Hutchinson, PT, MSCS

The director of the Multiple Sclerosis Achievement Center in Sacramento discussed 3-year data from an assessment of the program, outlining key findings and future research efforts. [WATCH TIME: 6 minutes]

Incorporating Telehealth Into the MS Care Model: Marisa McGinley, DO

The staff neurologist at the Mellen Center for Multiple Sclerosis Treatment and Research at Cleveland Clinic shared her perspective on the use of telemedicine in MS care, what challenges it can address, and the need to optimize its use. [WATCH TIME: 6 minutes]

COVID-19 Vaccinations and Multiple Sclerosis DMTs: Amit Bar-Or, MD, FRCPC, FAAN, FANA

The chief of the Multiple Sclerosis Division at the Perelman School of Medicine, University of Pennsylvania, discussed recommendations for COVID-19 vaccination in this patient population, specifically for those on disease-modifying therapies. [WATCH TIME: 2 minutes]

Evaluating Nutritional Health and Care for Patients With Multiple Sclerosis

Mona Bostick, RDN, LDN, MSCS, gave her perspective on nutrition in MS, popular elimination diets, and the role registered dietitians can play in the multidisciplinary care model.

Physical, Cognitive, and Social Programs for Patients With MS: Brian Hutchinson, PT, MSCS

The director of the Multiple Sclerosis Achievement Center outlined the design of the wellness programs, which are held in 2 different formats. [WATCH TIME: 4 minutes]

Discussing COVID-19 Vaccinations and Disease-Modifying Therapies in Multiple Sclerosis

Amit Bar-Or, MD, FRCPC, FAAN, FANA, commented on his presentations at CMSC 2021, one of which focused on COVID-19 vaccination, which experts do not believe poses risks for those on disease-modifying therapies.

Discontinuing Disease-Modifying Therapies in Multiple Sclerosis: Deborah Miller, PhD

The staff member at the Mellen Center for Multiple Sclerosis discussed reasons why patients may stop treatment, as well as strategies for maintaining communication with the healthcare team in the event of discontinuation. [WATCH TIME: 5 minutes]

Wellness Programs in Multiple Sclerosis Elicit ‘Stepwise’ Changes

Brian Hutchinson, PT, MSCS, commented on the Multiple Sclerosis Achievement Center program, which includes patient data spanning a 3-year period.

Talking Transitional Readiness for Teens With Multiple Sclerosis: Vikram Bhise, MD

The associate professor of pediatrics and neurology at Rutgers–Robert Wood Johnson Medical School commented on the need to recognize when adolescent patients are ready to learn more about their condition. [WATCH TIME: 5 minutes]

Clinicians’ Role in Ensuring Transitional Readiness in Pediatric MS

Vikram Bhise, MD, outlined useful questions to include in conversation when discussing the transition to adulthood for patients with pediatric multiple sclerosis.

Common Themes and Conversational Strategies for Pediatric MS Care Transition

Vikram Bhise, MD, discussed findings recently presented at CMSC 2021, where teenagers with multiple sclerosis were interviewed to identify perceptions of QOL during the transition to adulthood.

Dietitians and the Multidisciplinary MS Care Tea m: Mona Bostick, RDN, LDN, MSCS

The founder of Food Matters 365, in Greensboro, North Carolina, commented on the benefits of adding a dietitian to the healthcare team for patients with multiple sclerosis. [WATCH TIME: 3 minutes]

Transition Readiness, Quality of Life in Pediatric Multiple Sclerosis: Vikram Bhise, MD

The associate professor of pediatrics and neurology at Rutgers–Robert Wood Johnson Medical School discussed findings from a qualitative study that aimed at understanding priorities and concerns within this patient population during a transitional period.