Transitioning Sleep Schedules for School in Pediatric Patients: Carol Rosen, MD
September 15th 2022The professor of pediatrics at Case Western University discussed the complexities and negative effects for children drastically change their sleep schedules as school begins. [WATCH TIME: 3 minutes]
Increased Tau Burden Observed in Abnormal Central Vascular Hemodynamics
September 15th 2022Patients who demonstrated increased central pulse pressure and forward wave amplitude had greater entorhinal tau burden. These measures were not associated with amygdala, inferior temporal, nor precuneus tau burden.
Tolerizing MS Vaccine Displays Efficacy in Model of Relapsing-Remitting Multiple Sclerosis
September 14th 2022Results from a study provide a link between the association of multiple sclerosis and Epstein-Barr virus which could pave the way in the future for the development of new MS therapies.
The Future of Clinical Care with New Antiseizure Medication: Christopher Elder, MD
September 14th 2022An overview of the shifting landscape of antiseizure medication and various neurostimulation devices is shared by the clinical assistant professor of neurology in the Comprehensive Epilepsy Center at NYU Langone Health. [WATCH TIME: 5 minutes]
Cognitive Training With Constant Therapy Shows Feasibility in Early-Stage Alzheimer Disease
September 14th 2022Long-term use of the Constant Therapy program was feasible in a patient population with Alzheimer disease, as shown by the rate of adherence (80%) and use of the program over 24 weeks.
Rituximab Displays Superiority to Azathioprine, Mycophenolate Mofetil as Initial NMOSD Treatment
September 13th 2022Among a cohort of more than 300 patients in China, those with APQ4 positive NMOSD reported a significantly lower risk of relapse among those treated with rituximab compared with the other groups.
LIFT-AD Study Amended to Assess Alzheimer Disease Agent Fosgonimeton as Monotherapy
September 13th 2022In a previous phase 2 study, patients treated with fosgonimeton alone demonstrated potentially beneficial change in ERP P300 latency, as well as cognitive improvement, compared with placebo at 26 weeks.
Future Implications, Outlook of New CDC Developmental Milestone Guidelines: Paul Lipkin, MD
September 13th 2022The director of medical outpatient services at the Kennedy Krieger Institute discussed the long-term effects of the updated developmental milestone guidelines and the need to judge children based on the 75th percentile. [WATCH TIME: 7 minutes]
FDA Accepts Application for Trofinetide in Rett Syndrome
September 12th 2022The treatment, previously known as NNZ-2566, is supported by data from the LAVENDER study. With no plans to hold an advisory meeting, the agency set a PDUFA date of March 12, 2023, for the Acadia Pharmaceuticals product.
Differences in Approaches to Pediatric and Adult Sleep Disorders: Jodi A. Mindell, PhD
September 10th 2022The associate director of the Sleep Center at Children’s Hospital of Philadelphia detailed the similarities and differences in how sleep disorders are viewed between children and adults. [WATCH TIME: 4 minutes]
AT-GAA’s Conceivable Benefits for Pompe Disease and the Need for More Options
September 9th 2022Barry J. Byrne, MD, PhD, the associate chair of pediatrics and director of the Powell Gene Therapy Center at the University of Florida; and the chief medical advisor to the Muscular Dystrophy Association, offered his perspective on the upcoming FDA decision on AT-GAA (Amicus Pharma).
Insomnia Alone Linked to Worsened Symptoms and Impairments Than OSA Alone in Military Personnel
September 8th 2022Similarly, the prospective observational data of active duty military individuals showed that comorbid obstructive sleep apnea and insomnia resulted in worsened symptoms and sleep-related impairments.
AI’s Potential to Help Improve Insomnia Care: Anuja Bandyopadhyay, MD
September 8th 2022The assistant professor of clinical pediatrics at Indiana University School of Medicine, and the chair of the AASM’s Artificial Intelligence in Sleep Medicine Committee, discussed the potential of AI to progress care paradigms in insomnia. [WATCH TIME: 2 minutes]