AUPN Leadership Minute Episode 37: International Physicians in Neurology
September 12th 2023Episode 37 of the AUPN Leadership Minute features David G. Standaert, MD, PhD, of the University of Alabama at Birmingham; and Erica A. Schuyler, MD, of the University of Connecticut. [WATCH TIME: 5 minutes]
Collaborative Efforts for Health Equity in Alzheimer Disease Genetic Research: Adam Naj, PhD
September 12th 2023The genetic epidemiologist at the University of Pennsylvania discussed a recent study that highlighted the importance of diverse samples in genetic research for Alzheimer disease in helping to uncover hidden genetic risk factors. [WATCH TIME: 2 minutes]
AQP4-IgG Seropositive NMOSD and Systemic Lupus Erythematosus Shown to Overlap
September 12th 2023A recent systematic review showed that AQP4+NMOSD in patients with systemic lupus erythematosus can mimic neuropsychiatric manifestations, frequently occur after the onset of lupus or may predate, and necessitate indefinite treatment.
Treatment Effect of Neflamapimod Enriched When Excluding High P-Tau181 Level Patients
September 11th 2023The combined preclinical and clinical data with neflamapimod suggest the therapy has potential to be the first disease-modifying treatment for dementia with Lewy Bodies, demonstrating a positive impact on cognition, function, and mobility.
Nerivio Remote Electrical Neuromodulation Device Safe to Treat Migraine During Pregnancy
September 11th 2023Treatment with Nerivio did not differ from controls in outcomes of newborn weight, miscarriage rate, preterm birth rate, birth defect rate, stillbirths, and rate of newborns meeting developmental milestones 3 months postnatal.
Efforts Made to Improve the Rett Syndrome Behavior Questionnaire
September 11th 2023The Rett Syndrome Behavior Questionnaire’s implementation as global outcome measure in FDA-approved trials was the result of its comprehensive nature since it includes behavior-related symptom questions as well as questions for regular behaviors.
SomnoRing Appears Usable and Acceptable to Assess Sleep Health in Diverse Populations
September 10th 2023Recent research highlights how advanced technology like remote monitoring devices or wearables and smartphone-based apps for sleep health can be delivered at the point of care to meet the needs of patients.
Memory Consolidation in Epilepsy Enhanced During Sleep With Deep Brain Stimulation
September 8th 2023Researchers developed a novel “closed-loop” system that delivered electrical pulses in a brain region to synchronize brain activity recorded from another region in the brain to improve memory.
Antinuclear Antibodies Associated With Higher Disability and Disease Severity in NMOSD
September 8th 2023Antinuclear antibodies seem to be more associated with severe disease activity and poor prognosis among patients with NMOSD, which further implies that they may be potentially used as a prognostic marker for the disease.
Reframing the Communication of Lifestyle Changes for Migraine Management: Elizabeth Seng, PhD
September 8th 2023The associate professor at Yeshiva University and Albert Einstein College of Medicine explored the challenge of discussing lifestyle changes for patients with migraine, noting that lifestyle modifications can be a valuable addition to migraine treatment. [WATCH TIME: 3 minutes]
Rapid Administration of Diazepam Results in Improved Seizure Cluster Cessation, Shorter Seizures
September 7th 2023Treatment with diazepam nasal spray resulted in a statistically significant change in time between seizure clusters, potentially reflecting a beneficial effect of intermittent rescue therapy.
Autonomic Dysfunction Significantly Associated With Decreased Quality of Life in NMOSD and MS
September 7th 2023Findings showed that autonomic symptom burden was slightly more severe in patients with multiple sclerosis compared with those with NMOSD, although the difference was not statistically significant.
FDA Issues Ravulizumab Complete Response Letter for NMOSD, Citing Needed Changes to REMS Program
September 6th 2023The agency requested modifications to the REMS program, seeking validation of patients’ meningococcal vaccination status and prophylactic administration of antibodies prior to giving ravulizumab treatment.