Videos

Genetic Testing for Patients with ALS

The senior investigator at the National Institutes of Neurological Disorders and Stroke spoke about new opportunities for research into brain lesions and microglia.

Richard S. Bedlack, MD, PhD, MS;Ammar Al-Chalabi, MB, ChB, PhD;Jinsy A. Andrews, MD, MSc;Jeremy M. Schefner, MD, PhD

Diagnostic Criteria and Staging Systems in ALS

Experts in neurology give insight into recent advancements in genetic testing for amyotrophic lateral sclerosis (ALS) and discuss what factors to consider when offering it to patients.

Richard S. Bedlack, MD, PhD, MS;Ammar Al-Chalabi, MB, ChB, PhD;Jinsy A. Andrews, MD, MSc;Jeremy M. Schefner, MD, PhD

Drugs and Biomarkers in Development for Pediatric MS

A panel of experts considers the usefulness of diagnostic criteria and disease staging systems for patients with amyotrophic lateral sclerosis (ALS) as entry criteria for clinical trials.

Lauren B. Krupp, MD;Tanuja Chitnis, MD

Defining Treatment Failure in Pediatric MS

Expert neurologists discuss drugs in development for pediatric multiple sclerosis and consider the potential for biomarkers to monitor treatment response or new disease activity in the future.

Lauren B. Krupp, MD;Tanuja Chitnis, MD

Providing Nonoral Migraine Care With Intranasal DHE: Jessica Ailani, MD

Lauren B. Krupp, MD considers how treatment failure in pediatric multiple sclerosis may be defined as disease relapse, new or enlarging legions, inability to tolerate treatment, or lack of adherence.

Jessica Ailani, MD

Targeting Progressive MS Symptoms: Kathy Zackowski, PhD, OTR

The director of the MedStar Georgetown Headache Center spoke to the efficacy and application of a new formulation of the longstanding agent dihydroergotamine in the treatment of migraine.

Kathy Zackowski, PhD, OTR

Early, Aggressive Therapy for Relapsing-Remitting MS

The senior director of patient management, care, and rehabilitation research at the National MS Society discussed symptoms of MS that need more research, as well as other factors impacting care, such as comorbidities.

Scott Newsome, DO, MSCS, FAAN;Patricia K. Coyle, MD;Robert Fox, MD;Clyde E. Markowitz, MD

Differentiating Between the Subtypes of MS

The rationale for initiating aggressive therapy early on to treat patients who present with relapsing-remitting multiple sclerosis.

Scott Newsome, DO, MSCS, FAAN;Patricia K. Coyle, MD;Robert Fox, MD;Clyde E. Markowitz, MD

Management of Cognitive Issues of MS During COVID-19

An overview of the clinical subtypes of multiple sclerosis and factors that help neurologists distinguish between each type for an appropriate diagnosis.

June Halper, MSN, MSCN;Mary Ann Picone, MD

Maintaining a Healthy Diet and Exercise for Patients With MS

Strategies for diagnosing and treating cognitive issues of multiple sclerosis during COVID-19.

June Halper, MSN, MSCN;Mary Ann Picone, MD

Studying the Trajectory of Cognitive Decline: Richard Gershon, PhD

Maintaining a healthy diet and exercise when combating multiple sclerosis.

Richard Gershon, PhD

Addressing Specific Social Determinants of Health in Epilepsy: Joseph Sirven, MD

The vice chair for research at the Northwestern University Feinberg School of Medicine discussed how the cognitive mobile toolbox can be used to assess cognition in all populations.

Joseph Sirven, MD

April 25th 2021

The Long-Term Efficacy of Inebilizumab in NMOSD: Bruce Cree, MD, PhD, MAS

The professor of neurology at Mayo Clinic detailed ways to address social determinants of health and the gaps in care for patients with epilepsy.

Bruce Cree, MD, PhD, MAS, FAAN

April 24th 2021

Stroke Common Cause of Seizures, Inebilizumab Demonstrates Continued Benefits, Fremanezumab Safe in Patients With CV Risk

The clinical research director at the UCSF Multiple Sclerosis Center discussed the findings of the long-term open-label assessment of inebilizumab in neuromyelitis optica spectrum disorder.

NeurologyLive® Staff

April 24th 2021

Advantages of Fremanezumab Among CGRP Migraine Agents: Stephanie J. Nahas, MD

Neurology News Network for the week ending April 24, 2021.

Stephanie J. Nahas, MD

Genetic Testing and Diagnostic Delay in SMA

The associate professor and director of the Headache Medicine Fellowship Program at Thomas Jefferson University detailed the reasons fremanezumab stands out among a crowded migraine treatment landscape.

Crystal Proud, MD;Claudia Chiriboga, MD, MPH;Basil Darras, MD;Tom Crawford, MD ;Carolina Tesi Rocha, MD

Signs of Symptoms of Spinal Muscular Atrophy

Basil Darras, MD considers the impact of genetic testing for SMN1 deletion and SMN2 copy numbers in potential patients and discusses best practices to prevent diagnostic delay.

Crystal Proud, MD;Claudia Chiriboga, MD, MPH;Basil Darras, MD;Tom Crawford, MD ;Carolina Tesi Rocha, MD

Evaluating the Potential of Vultrisiran

Expert neurologist Carolina Tesi Rocha, MD reviews the signs and symptoms of SMA and their impact on the delay of developmental milestones in infants and toddlers.

John L. Berk, MD;P. James B. Dyck, MD;Michael J. Polydefkis, MD;Thomas H. Brannagan III, MD;Ronald Witteles, MD

Benefits of TTR Gene Silencers

Expert discussion on the recent topline results released for vutrisiran in the HELIOS-A trial.

John L. Berk, MD;P. James B. Dyck, MD;Michael J. Polydefkis, MD;Thomas H. Brannagan III, MD;Ronald Witteles, MD

Nipocalimab Shows Promise as Myasthenia Gravis Treatment: Jeffrey Guptill, MD, MS, MHS

Discussion on the role of TTR protein stabilizers and gene silencers for treating hereditary ATTR amyloidosis.

Jeffrey Guptill, MD, MS, MHS

Age Considerations: Patients With Nonactive MS Progression

The associate professor of neurology and neurologist at Duke University discussed the positive results of nipocalimab, a monoclonal antibody, in patients with myasthenia gravis.

Bruce Cree, MD, PhD, MAS, FAAN;Joseph R. Berger, MD;Kristen Krysko, MD;Fred D. Lublin, MD;Robert Fox, MD

Improving PAP Adherence in Younger Patients With OSA: William Noah, MD

Considerations regarding age in treatment decisions in patients with nonactive multiple sclerosis progression.

William Noah, MD

Atogepant Continues to Shine in Phase 3 ADVANCE Study: Lawrence Severt, MD, PhD

The director and founder of the Sleep Centers of Middle Tennessee discussed trends in positive airway pressure adherence that his center’s research has revealed.

Lawrence Severt, MD, PhD

Monitoring Response in Progressive MS

The director at AbbVie discussed a number of abstracts presented at AAN 2021 involving atogepant and its phase 3 ADVANCE study.

Bruce Cree, MD, PhD, MAS, FAAN;Joseph R. Berger, MD;Kristen Krysko, MD;Fred D. Lublin, MD;Robert Fox, MD

Applications of Telestroke and Teleneurology: Jason Poon, MD

Experts discuss how they monitor response to multiple sclerosis therapies and disease progression.

Jason Poon, MD

Comparing Sublingual and Subcutaneous Apomorphine

The neurologist at University of Utah discussed his research presented at AAN 2021 on telestroke’s accuracy of differentiating between acute ischemic stroke and mimics.

Laxman Bahroo, DO;Mindy K. Bixby, DO

Sublingual Apomorphine for Managing PD OFF Episodes

Mindy K. Bixby, DO and Laxman Bahroo, DO compare subcutaneous and sublingual apomorphine hydrochloride and discuss important factors to consider when selecting a formulation.

Laxman Bahroo, DO;Mindy K. Bixby, DO

The Safety Profiles of Therapies for Migraine

Experts in the management of Parkinson’s Disease OFF episodes provide insight into the sublingual formulation of apomorphine hydrochloride and discuss differences in its safety and efficacy profiles.

Philippa Cheetham, MBChB, MRCS, MD, FRCS;Jill Dehlin, RN;Jessica Ailani, MD