Amyloid Precursor Protein and Amyloid Beta Species in Alzheimer’s Disease
May 13th 2024The panel provides an overview of amyloid precursor protein (APP) and the generation of amyloid β (Aβ) peptides, Aβ42 and Aβ40, while also discussing which soluble or insoluble Aβ species (monomers, oligomers, protofibrils, or amyloid plaques) contribute to neuronal damage and the clinical manifestation of Alzheimer's disease.
Overlooked Neurological Features Present in Long COVID: Svetlana Blitshteyn, MD, FAAN
May 13th 2024The director of Dysautonomia Clinic talked about advocating for recognition and research into neurological symptoms that have long been overlooked in patients with Long COVID. [WATCH TIME: 3 minutes]
Recent Progress in Advancing Gene Therapy for Parkinson Disease: Russell Lonser, MD
Published: May 7th 2024 | Updated: May 23rd 2024The director for the Gene Therapy Institute at The Ohio State University talked about the latest developments in gene therapy for patients with Parkinson disease. [WATCH TIME: 4 minutes]
Understanding the Impact of Data Analysis on Preventive Migraine Treatment: Jessica Ailani, MD
May 7th 2024The director of the MedStar Georgetown Headache Center discussed the importance of maintaining hope and providing understanding of patients' frustrations in their treatment journey for migraine. [WATCH TIME: 5 minutes]
Understanding the Therapeutic Potential of Nipocalimab: Katie Abouzahr, MD
Published: May 6th 2024 | Updated: May 6th 2024The vice president, Autoantibody Portfolio and Maternal Fetal Immunology Disease Area Leader, Johnson & Johnson, provided perspective on the unique molecular structure of nipocalimab seen across nonclinical and clinical studies. [WATCH TIME: 3 minutes]
Importance of Early Diagnosis of Alzheimer’s Disease
Published: May 6th 2024 | Updated: May 6th 2024Key opinion leaders emphasize the significance of early diagnosis in Alzheimer's disease, as it allows patients to make autonomous decisions and access early treatment options, including potential participation in clinical trials.
Apolipoprotein E4 in Alzheimer’s Disease
Published: May 6th 2024 | Updated: May 6th 2024Sharon Cohen, MD, and Marwan Sabbagh, MD, differentiate between the preclinical, prodromal, and dementia stages of Alzheimer's disease (AD), and highlight known risk factors, including the contribution of ApoE gene polymorphism and copy numbers.
A Call to Action to Address Disparities in Multiple Sclerosis Care: Jaime Imitola, MD
Published: May 6th 2024 | Updated: May 6th 2024The chief of the Division of MS and Neuroimmunology at UConn Health talked about the challenges with access to care in multiple sclerosis, particularly for marginalized communities, despite significant progress made in the field over the past decades. [WATCH TIME: 4 minutes]
Addressing Potential Causes of Burnout Through Productive Solutions: Neil Busis, MD
Published: May 3rd 2024 | Updated: May 3rd 2024The associate chair for technology and innovation at the NYU Grossman School of Medicine provided commentary on a study from AAN 2024 that examined the driving factors behind burnout in neurology departments. [WATCH TIME: 4 minutes]
Ravulizumab’s Long-Term Efficacy and Safety as NMOSD Treatment: Sean Pittock, MD
May 2nd 2024The director for the Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology provided an overview of the open-label extension of the phase 3 CHAMPION-NMOSD trial and how the newly approved ravulizumab fits with other NMOSD treatments. [WATCH TIME: 4 minutes]