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Complement Inhibitors for Treatment of Generalized Myasthenia Gravis

Key Takeaways

  • Complement inhibitors target the C5 component of the complement cascade, preventing membrane attack complex formation and reducing neuromuscular junction damage.
  • Clinical trials show significant efficacy in improving muscle strength and reducing symptoms in gMG patients.
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Panelists discuss how complement inhibitors work to treat generalized myasthenia gravis (gMG), evaluating their efficacy and safety profiles based on FDA approvals and clinical experience.

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