Episode 106: Potential Role of Stathmin-2 in Amyotrophic Lateral Sclerosis

Cathleen Lutz, PhD

Episode 106 of the NeurologyLive^® Mind Moments^® podcast is now live! Scroll down to listen or click here to subscribe on your favorite streaming service.

The Mind Moments podcast features exclusive interviews with leaders in the field discussing the latest research and disease management strategies across the breadth of neurology, including epilepsy, multiple sclerosis, Parkinson disease, dementia, sleep disorders, and more.

Episode 106, "Recapping Conversations in Neurology From 2023" features a conversation with Cathleen Lutz, PhD, vice president of the Rare Disease Translational Center at the Jackson Laboratory, who provided comment on a recently published study on the role of stathmin-2 loss leads to in patients with amyotrophic lateral sclerosis (ALS). Lutz offered insight on the role stathmin-2 may have in this disease, the questions that still remain, and whether restoration of stathmin-2 may be an attractive therapeutic approach. Furthermore, she spoke on the potential of this protein as a disease-modifying biomarker and whether it may be incorporated in trials in the near future. 

The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here:

• FDA Clears Phase 2 KYSA-7 Study of CAR T-Cell Therapy in Refractory Progressive Multiple Sclerosis
• Dyne Reports Positive Phase 1/2 Data for Duchenne Agent DYNE-251
• Parkinson Gene Therapy AB-1005 Meets Primary End Point in Phase 1b Trial
• VISIONARY-MS Trial Reports CNM-Au8 Improves Vision and Cognition in Multiple Sclerosis

This episode is brought to you by Medical World News, a streaming channel from MJH Life Sciences^®. Check out new content and shows every day, only at medicalworldnews.com

EPISODE BREAKDOWN

• 1:15 – Idea behind studying stathmin-2
• 2:45 – Overviewing study results
• 7:05 – Next steps in extending this research
• 8:40 – Neurology News Minute
• 11:30 – Stathmin-2's connection with neurofilament light
• 12:55 – Potential of stathmin-2 as ALS-specific biomarker
• 14:45 – Future use of stathmin-2 in clinical trials
• 15:30 – Closing thoughts

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