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Articles

Phase 2b trial results showed Descartes-08, a CAR-T therapy, achieved sustained efficacy and a strong safety profile in myasthenia gravis, with notable responses in biologic-naïve patients and no major safety concerns over 12 months.

CAR-T Therapy Descartes-08 Demonstrates Efficacy, Safety in Phase 2 Trial of Myasthenia Gravis

Take 5 minutes to catch up on NeurologyLive®'s highlights from the week ending April 11, 2025. 

NeurologyLive® Friday 5 — April 11, 2025

Cleveland Clinic’s $1.1 billion Neurological Institute, opening in 2027, will revolutionize neurological care with a state-of-the-art, patient-centered design integrating advanced technology and innovative care solutions.

Revolutionizing Neurology Care: Previewing Cleveland Clinic’s New Neurological Institute

In one of the longest trials of brain stimulation in Alzheimer disease, repetitive transcranial magnetic stimulation led to a reduced decline in CDR-SB, as well as positive impacts on cognitive function and functional abilities.

Sinaptica’s Transcranial Magnetic Stimulation Device Meets Primary End Point in Phase 2 Trial of Alzheimer Disease

Marco Meglio, Assistant Managing Editor for 

, has been with the team since October 2019. Follow him on Twitter 

Videos

The neuroradiologist at Mayo Clinic provided clinical insights on the controversy with two recently published Alzheimer criteria, with one diagnosing the disease based on biomarkers alone vs clinical symptoms. [WATCH TIME: 4 minutes]

Educating the Clinical Community on Differences in Alzheimer Diagnostic Criteria: Clifford Jack, MD

Clinical associate professor of neurology and neurosurgery at NYU Langone Health. 

The clinical associate professor of neurology and neurosurgery at NYU Langone Health emphasized the importance of rapid, targeted blood pressure reduction and bundled care to improve outcomes in patients with intracerebral hemorrhage. [WATCH TIME: 4 minutes]

The Key Role of Early and Balanced Blood Pressure Control in ICH Management: Kara R. Melmed, MD

The Melissa and Paul Anderson President’s Distinguished Professor of Neurology, Perelman School of Medicine, University of Pennsylvania discussed evolving insights into the cellular immunology of multiple sclerosis. [WATCH TIME: 4 minutes]

Understanding the Cellular Drivers of MS Progression and Treatment Response: Amit Bar-Or, MD, FRCPC, FAAN, FANA

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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Contemporary Data on Treating Multiple Sclerosis Exacerbations

Escalation Versus Induction Therapy in Relapsing Multiple Sclerosis

Goals of Therapy for Relapsing MS

The Gut Microbiota and Risk of Relapse in MS

Repository Corticotropin Injection for Relapsing MS

Relapse Recovery and Outcomes in MS

Repository Corticotropin Injection for RRMS

Response to Cladribine Tablets in RRMS

Ocrelizumab for Relapsing MS

Treating Relapsing MS With Ocrelizumab

Ofatumumab for Relapsing MS

Optimizing Outcomes for Patients With MS

Clinical

EMD-22-NRD0193 - /clinical/multiple-sclerosis

 video series brings together pairs of expert clinicians and physicians to independently provide their insights on the latest and most up-to-date clinical care for specific neurologic diseases and disorders.