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Articles

A recent study presented at the 2025 AD/PD Conference identified key modifiers of Alzheimer disease onset in amyloid precursor protein duplication carriers. 

Genetic Risk Factors Influence Age at Onset in Autosomal Dominant Alzheimer Disease

A phase 2a biomarker trial of xanamem presented at AD/PD 2025 suggests the drug may help slow clinical decline in patients with Alzheimer who have elevated levels of plasma pTau181.

Xanamem Shows Potential in Slowing Alzheimer Progression in Patients With Elevated Plasma pTau181

A recent study reported that silmitasertib, an investigational drug currently in development for cancer, may help reduce motor deficits and neuropathology in a Huntington disease.

Therapeutic Potential of Silmitasertib Observed in Huntington Disease Mouse Model

Although valiltramiprosate failed to distinguish itself from placebo on the primary end point, the drug performed significantly better among mild MCI participants vs those with mild Alzheimer disease.

Valiltramiprosate Demonstrates Greater Promise in Milder Forms of Alzheimer Disease, Phase 3 APOLLOE4 Study Shows

Senior vice president of research at The ALS Association. 

Videos

The senior vice president of research at The ALS Association talked about a multidisciplinary session presented at the 2025 MDA Conference that highlighted diverse strategies for neural repair, from pharmacological targets to noninvasive brain stimulation. [WATCH TIME: 6 minutes]

Exploring Multimodal Approaches to Neural Regeneration: Kuldip Dave, PhD

Marco Meglio, Assistant Managing Editor for 

, has been with the team since October 2019. Follow him on Twitter 

In this final episode, neurologists discuss the role of advanced imaging, like OCT, in diagnosing and managing MS, emphasizing the need for further research to optimize its clinical application. [WATCH TIME: 2 minutes]

Bridging Neurology and Ophthalmology in Multiple Sclerosis Research

A pair of neurologists provide clinical insight on the difficulties with identifying and differentiating optic neuritis in various autoimmune conditions like multiple sclerosis and neuromyelitis optica spectrum disorder. [WATCH TIME: 4 minutes]

Challenges in Diagnosing Optic Neuritis in MS and MOGAD

In this third episode, experts delve into the evolving role of optic neuritis and the central vein sign in refining multiple sclerosis diagnosis, highlighting their significance in distinguishing MS from other conditions and ensuring accurate patient care. [WATCH TIME: 3 minutes]

Educating the Clinical Community on Changes to MS Diagnostic Criteria

NeurologyLive is your direct connection to the latest neurology news and interviews with expert neurologists in multimedia formats.

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Alzheimer and circulating cholesterol linked, obesity has a big impact on MS, mild traumatic brain injury difficulties persist, and other recent findings are summarized here.

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Neurology News: Alzheimer Disease, MS, and More