NeurologyLive® Year in Review 2022: Most-Listened Mind Moments® Episodes

Every other Friday, the NeurologyLive^® team publishes a new episode of our podcast, Mind Moments^®. The show features guests who are experts in the clinical care of patients, executives of pharmaceutical companies, top researchers and investigators, and key voices in the advocacy communities.

By the end of 2022, we'll have posted 30 episodes of the podcast that highlighted the latest updates, advances, and major news developments that took place this year in neurology. From dementia and neurodegenerative disease to seizures and demyelinating disorders, the discussions covered FDA decisions, hot topics in care, and the state of treatment for neurologic disease. Some shows included one-on-one discussions, while others tried to offer a high-level view of the biggest news from medical meetings across the globe.

Here, we'll highlight the most-listened-to episodes of the podcast that appeared on NeurologyLive^® this year. Click play to listen to any one of these episodes.

1. Episode 56: Epstein-Barr Virus's Relationship With Multiple Sclerosis

LISTEN TIME: 32 minutes

Episode 56 features an exclusive interview with Bridget A. Bagert, MD, MPH, director of the Ochsner Multiple Sclerosis Center, and an investigator in the clinical study of the Epstein-Barr virus (EBV)-targeted agent, ATA188 (Atara Biotherapeutics). She offered her perspective on the recent data from Ascherio et al on the relationship between EBV and multiple sclerosis (MS) that suggest it may be a root cause of the disease, as well as background on the decades of research that have led to this point and the potential of therapies that target EBV and the B cells it infects for patients with MS.

2. Episode 68: Updates in Essential Tremor Care

LISTEN TIME: 27 minutes

Episode 68 features an exclusive interview with Rajesh Pahwa, MD, professor of neurology and director of the Parkinson's Disease and Movement Disorder Center at the University of Kansas Medical Center. He spoke about the current state of treatment for essential tremor, including the therapeutic and surgical options for this population, and shared his perspective on the latest advances in clinical care and diagnosis, the role of the patient-physician relationship, and the research into the disease's underlying processes.

3. Episode 55: Treating Headache in the Emergency Department

LISTEN TIME: 23 minutes

Episode 55 features an exclusive interview with Anne-Maree Kelly, MD, MClinEd, FACEM, senior emergency physician at Western Health; director of the Joseph Epstein Centre for Emergency Medicine Research; professorial fellow at the University of Melbourne; and adjunct professor at the Australian Centre for Health Law Research at Queensland University of Technology. She shared her clinical experience treating patients with headache and migraine in the emergency department (ED), offering insight into the factors that influence patient outcomes and the vital need for consensus international guidelines for ED migraine care.

4. Special Episode: Daridorexant Approved for Insomnia

LISTEN TIME: 12 minutes

This special episode features an exclusive interview with Thomas Roth, PhD, director of the Sleep Disorders and Research Center at Henry Ford Hospital; professor of psychiatry at Wayne State University School of Medicine; and clinical professor of psychiatry at University of Michigan College of Medicine. Roth, who was an investigator in the clinical development studies of the newly approved Idorsia therapy, offered insight into the known efficacy and safety profiles, as well as some context to its potential impact on the therapeutic landscape of insomnia.

5. Episode 57: Invisible Symptoms: Cognition and MS

LISTEN TIME: 39 minutes

Episode 57 features an exclusive interview with Dhanashri P. Miskin, MD, clinical assistant professor of neurology at Thomas Jefferson University Hospitals. She offered her insight into the role that cognitive impairment plays as a symptom of multiple sclerosis, the current approach to treatment and management for patients, and what challenges remain for the field to address.

6. Episode 61: 2022 AAN Annual Meeting Highlights

LISTEN TIME: 32 minutes

Episode 61 features interviews with a number of individuals who presented data and spoke at the American Academy of Neurology Annual Meeting, on topics ranging from COVID-19's clinical presentation, overall trends in the care of patients with multiple sclerosis, the potential of regenerative medicine in traumatic brain injury, the real-world and long-term use of new therapy for Lennox-Gastaut syndrome, the optimal timing for the newest therapy in neuromyelitis optica spectrum disorder, the Axon Registry and incorporating EHR information into its data collection, and the impact of the pandemic on clinician burnout and mental health. Those featured include Jennifer Frontera, MD; Stephen Krieger, MD; Peter McAllister, MD; Kelly Knupp, MD, MSCS; Bruce Cree, MD, PhD, MAS; Shrujal Baxi, MD, MPH; and Indu Subramanian, MD.

7. Episode 69: The Widespread Effects of DMT Waste in Multiple Sclerosis

LISTEN TIME: 55 minutes

Episode 69 features an exclusive interview with Darin T. Okuda, MD, professor of neurology and director of Neuroinnovation and the Multiple Sclerosis & Neuroimmunology Imaging Program at The University of Texas Southwestern Medical Center at Dallas; and Karin Cook, senior vice president of medical strategy and clinical ethnographer, Heartbeat Medical Communications. The pair spoke about their research into the wasted costs associated with disease-modifying therapies (DMTs) for patients with multiple sclerosis, what they've observed at their center, the wide-reaching impact of this waste on the healthcare continuum, and the future solutions that are being worked on for this problem.

8. Episode 73: The Role of Palliative Care in Neurology

LISTEN TIME: 40 minutes

Episode 73 features an exclusive interview with Ambereen Mehta, MD, MPH, palliative care physician and assistant professor of medicine at Johns Hopkins Bayview Medical Center. She joined the show to discuss palliative care and its evolving role in the care paradigm for patients with chronic neurologic disease, as well as its history in the United States, how it differs from hospice care, and more.

9. Episode 71: Pediatric Sleep and School Start Times

LISTEN TIME: 31 minutes

Episode 71 features an exclusive interview with Chris Winter, MD, owner of Charlottesville Neurology and Sleep Medicine clinic and CNSM Consulting, and an author of several books on sleep. He shared his perspective on the state of pediatric sleep disorders, how the current system of schooling affects children's sleep, and the trends that are occurring in sleep research.

10. Episode 72: Updates in Epilepsy Treatment

LISTEN TIME: 32 minutes

Episode 56 features an exclusive interview with Christopher Elder, MD, clinical assistant professor of neurology, Comprehensive Epilepsy Center, NYU Langone Health. He joined the show to talk about the latest updates in the care of patients with epilepsy, the clinical therapeutic pipeline developments on the horizon, and the need to continue stressing conversations around sudden unexpected death in epilepsy (SUDEP).