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Addressing Neurogenic Bladder: Understanding Prevalence, Unmet Needs, and Effective Management

Clinical

Bladder Function 

Panelist discusses how treatment options for neurogenic bladder include pharmacological approaches such as anticholinergics, localized interventions such as botulinum toxin injections, and neuromodulation techniques (posterior tibial and sacral nerve stimulation). Surgery serves as a last resort when conservative treatments fail.

Treatments for Neurogenic Bladder

Video content above is prompted by the following: 

Please discuss the treatment options for neurogenic bladder.

Tamara Kaplan, MD, introduces a new video series highlighting the scope and treatment of neurogenic bladder.

Panelist discusses how the neuroanatomy of bladder function involves a sophisticated interplay between autonomic and somatic nervous systems. The bladder is controlled by parasympathetic nerves (S2-S4) for detrusor contraction, sympathetic nerves (T11-L2) for sphincter control, and somatic nerves for voluntary control via the pudendal nerve. This complex coordination enables both automatic storage and voluntary voiding through reciprocal innervation.

Lower Urinary Tract Overview

Panelist discusses how bladder dysfunction in neurological conditions requires attention, as it significantly affects patient quality of life and can indicate disease progression or complications. Neurologists face challenges in diagnosis and treatment due to overlapping symptoms, complex neural pathways involved, and the need to differentiate between multiple potential causes.

Neurogenic Bladder: Challenges in Diagnosis

Panelist discusses how a detailed patient history is critical for neurological lesion localization, helping physicians map symptoms to specific anatomical regions. Key bladder-related history focuses on urinary urgency, frequency, retention, and incontinence patterns, as these symptoms often indicate specific spinal cord or brain lesion locations that affect autonomic function.

Role of Patient History in Neurogenic Bladder Diagnosis

Panelist discusses how neurogenic bladder in neurological conditions manifests distinctly based on lesion location. Patients with multiple sclerosis typically experience detrusor overactivity and sphincter dyssynergia, leading to urgency and retention. Parkinson disease commonly presents with overactive bladder symptoms and nocturia due to impaired basal ganglia control. Cauda equina syndrome and lumbar disc herniation often result in detrusor areflexia and decreased sensation, causing retention and overflow incontinence.

Neurological Conditions and Bladder Dysfunction

Lasso - DMD Peers and Perspectives NSP-21-NRD0157

 video series brings together pairs of expert clinicians and physicians to independently provide their insights on the latest and most up-to-date clinical care for specific neurologic diseases and disorders.

Treatments for Neurogenic Bladder

EP: 1.Addressing Neurogenic Bladder: Understanding Prevalence, Unmet Needs, and Effective Management

EP: 2.Lower Urinary Tract Overview

EP: 3.Neurogenic Bladder: Challenges in Diagnosis

EP: 4.Role of Patient History in Neurogenic Bladder Diagnosis

EP: 5.Neurological Conditions and Bladder Dysfunction

EP: 6.Treatments for Neurogenic Bladder