Authors
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Summer 2024 – Letter From the EditorMary Ann Picone, MD, FAAN, FACP, provides a summary of her time at the recently held 2024 CMSC Annual Meeting.
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Advanced Parkinson Disease: Looking AheadPanelists look ahead in the management of advanced Parkinson disease and discuss the promise of different investigational therapies.
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Future Role of Neurofilament Light in ALS Drug Development, Clinical Trials: Rita Sattler, PhD, MScThe professor in the Department of Translational Neuroscience at Barrow Neurological Institute provided perspective on the approval of tofersen (Qalsody; Biogen) for patients with ALS and the ways neurofilament light will be used going forward. [WATCH TIME: 3 minutes]
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Evolution of Stroke Treatment on Display at ISC 2025: Andrei Alexandrov, MDThe professor and chair of the neurology department at the University of Arizonia, Phoenix, gave clinical insights on the notable progress in the stroke treatment world, highlighted by advances presented at the 2025 International Stroke Conference. [WATCH TIME: 3 minutes]
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Cenobamate's Efficacy in Drug-Resistant Epilepsy: Jacob Pellinen, MDThe assistant professor of neurology at University of Colorado School of Medicine discussed findings on the impact of cenobamate on hospital visits and emergency care for patients with drug-resistant epilepsy following surgery. [WATCH TIME: 3 minutes]
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Preclinical Research on CRISPR-Based Gene Editing for Alzheimer Disease Treatment: Brent D. Aulston, PhDThe postdoctoral fellow at the University of California San Diego discussed using CRISPR-based gene editing to alter the amyloid precursor protein gene in mice models with symptoms of Alzheimer disease. [WATCH TIME: 5 minutes]
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Addressing the Unmet Needs of Managing MS Symptoms: Michael Y. Sy, MD, PhDThe associate professor of clinical neurology at University of California, Irvine School of Medicine talked about addressing the critical unmet needs in disability progression among patients with multiple sclerosis. [WATCH TIME: 3 minutes]
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Spring Forward or Fall Back: Time-Change Sleep ProblemsBijoy E. John, MD, founder and medical director of Sleep Wellness Clinics of America (Nashville) and Sleep Fix Academy, discussed the health risks associated with daylight saving time changes.
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Questions Linger Around COVID-19’s OriginMike Hennessy Sr, Chairman and founder, MJH Life Sciences™, offers his perspective on the questions around the origin of COVID-19 and applauds the extensive efforts to produce vaccines.
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Feasibility of Incorporating an Interprofessional Student Program to Other Institutions, Universities: Stephanie Teixeira-Poit, PhDThe associate professor at the North Carolina Agricultural and Technical State University provided insight on the widespread feasibility of a new initiative that aims to teach and attract young professionals to the MS field. [WATCH TIME: 4 minutes]
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Future Research Efforts in Aging MSIn the final episode, Negroski gave closing thoughts on some of the major unmet needs in research regarding aging in MS, as well as some of the unanswered questions clinicians are still trying to figure out.
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Published Phase 3 Data Demonstrates Unprecedented Improvements in SMA Type 1 Compared With Natural HistoryThe senior vice president and chief medical officer at Novartis Gene Therapies shared his perspective on the recent clinical trial results for Zolgensma in SMA type 1.
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NeuroVoices: Tanya Simuni, MD, FAAN, on Using the Neuronal α-Synuclein Disease Integrated Staging System Framework to Advance Parkinson Disease StagingThe professor of neurology at Northwestern University Feinberg School of Medicine discussed the NSD-ISS and its potential to refine PD diagnosis and clinical trial selection through biomarker-driven staging.
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Building a Healthy Learning Environment for Young Medical Professionals: Alexandria Reynolds, PhDThe undergraduate program director at the University of South Carolina discussed the shift in teaching strategies for those in neurology and why more hands-on experience serves students better. [WATCH TIME: 5 minutes]
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Enacting Necessary Changes to the MS Care Model: Mona Bostick, RDN, LDN, MSCSDiscussing adaptations to the comprehensive care model in multiple sclerosis, the founder of MS Bites commented on the need to consistently incorporate dietitians. [WATCH TIME: 6 minutes]
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Future Plans and Clinical Promise of Inebilizumab in Myasthenia Gravis: Richard Nowak, MD, MSThe director of the myasthenia gravis clinic at Yale University provided additional insight on the MINT study of inebilizumab in myasthenia gravis, some of the subanalyses within, and next plans in the drug’s development. [WATCH TIME: 5 minutes]
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Using the Cognitive Stress Test to Distinguish Pre-MCI and Amnestic MCI: Leeron Nahmias, BSThe medical student at Nova Southeastern University provided insight on a new innovative tool called the Cognitive Stress Test that can help distinguish different cognitive states for older adults. [WATCH TIME: 6 minutes]
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Enhancing Initiation and Titration Strategies for Neuromodulation in Lennox-Gastaut Syndrome: Depobam Samanta, MD, MS, FAAP, FAESThe medical director of the Arkansas Children’s Comprehensive Epilepsy Program detailed advancements and strategies in using neuromodulation for LGS, as well as the future research needed to expand these approaches. [WATCH TIME: 4 minutes]
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CDC and FDA Announce Stroke Safety Concern Related to Pfizer-BioNTech Bivalent COVID-19 VaccineDespite previous data suggesting no link, the CDC and FDA will continue to review all evidence for possible increased risk of ischemic stroke.
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Empowering Patient Voice in Epilepsy Treatment and Strategies for Seizure Freedom: Patrick Kwan, MD, PhD, FRCPThe professor of neurology in the department of neuroscience at Monash University discussed implementation strategies for treatment approaches to achieve seizure freedom in patients with epilepsy. [WATCH TIME: 5 minutes]
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Paramagnetic Rim Lesions and Immune Profiling in Multiple Sclerosis Progression: Simon Thebault, MD, PhDThe assistant professor of neurology and neurosurgery at McGill University discussed the role of paramagnetic rim lesions as potential biomarkers of compartmentalized inflammation in MS. [WATCH TIME: 4 minutes]
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Using a Novel Educational Intervention to Improve Overall Knowledge of Headache: Sara Pavitt, MDThe chief of headache at UT Austin Dell Children’s Hospital provided insight on a new series designed to deliver longitudinal comprehensive pediatric headache education. [WATCH TIME: 3 minutes]
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The Realities of Gender-Targeted Therapeutics for Alzheimer Disease: Jessica Caldwell, PhDThe director of the Women’s Alzheimer’s Movement Preventer Center at Cleveland Clinic provided perspective on the possibility of gender-specific therapies to overcome disparities in Alzheimer disease. [WATCH TIME: 3 minutes]
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The Potential of Embolization as a Treatment Approach for Subdural Hematomas: Jason M. Davies, MD, PhDThe assistant professor of neurosurgery and biomedical informatics at the State University of New York at Buffalo talked about the efficacy and safety of using embolization as a promising treatment for subdural hematomas. [WATCH TIME: 3 minutes]
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Anti-CD20 Therapies for MSAhmed Obeidat, MD, PhD, Riley Bove, MD, Stephen Krieger, MD, and Erin Longbrake, MD, PhD, talk about the factors to consider when determining whether patients are candidates for anti-CD20 therapies.
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Understanding Stathmin-2’s Impact on ALS Motor and Sensory Denervation: Cathleen M. Lutz, PhDThe vice president of the Rare Disease Translational Center at the Jackson Laboratory discussed results from a recently published study reinforcing stathmin-2 as a potential therapeutic strategy for ALS. [WATCH TIME: 4 minutes]
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Building the Next Generation of Migraine Specialists: Rashmi B. Halker-Singh, MD, FAAN, and Paul Mathew, MD, DNBPAS, FAAN, FAHSThe chair and vice-chair of the Headache and Facial Pain Section of the American Academy of Neurology provided insight on projects they feel are needed to advance the care of patients with migraine-related disorders. [WATCH TIME: 4 minutes]
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Real-World Effectiveness and Safety of Monoclonal Antibodies in NMOSD: Amy Kunchok, MD, PhDThe staff neurologist at the Mellen Center for Multiple Sclerosis at Cleveland Clinic talked about findings from a real-world study assessing novel monoclonal antibodies in patients with NMOSD presented at ACTRIMS Forum 2024. [WATCH TIME: 4 minutes]
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Building Your Acute Migraine ToolboxPlagued by a long history of under- and inadequate treatment, clinicians have more options than ever to craft a personalized, effective plan for their patients.
