The Alzheimer’s Association International Conference (AAIC) is the largest international meeting dedicated to advancing dementia science. It convenes basic science and clinical researchers, next-generation investigators, clinicians, and the research community to share research discoveries toward preventing and treating Alzheimer disease.
Distinct Alzheimer Disease Subtypes Using Proteomic Fingerprints: Fiona Elwood, PhD
October 8th 2024The disease area stronghold leader in neurodegeneration at Johnson & Johnson discussed data presented at AAIC 2024 highlighting different subtypes of Alzheimer disease that may lead to more personalized treatments. [WATCH TIME: 4 minutes]
Therapeutic Potential of Combination Strategies to Treat Alzheimer Disease: Lloyd Tran, PhD
August 28th 2024The chairman and chief executive officer at Biomed discussed the additive benefits of combination therapy for Alzheimer disease, providing context on the strengths of different drugs and how it might lead to a more precision medicine approach. [WATCH TIME: 6 minutes]
Utility of Digital Twin AI-Generated Models to Improve Patient Selection in Alzheimer Trials
August 27th 2024Steve Herne, chief commercial officer at Unlearn, provided context on a recently conducted study assessing the company’s digital twin methodology AI tool to enhance the statistical certainty of Alzheimer trials.
Expanding the Potential to Treat Alzheimer Disease With RNA Therapeutics: Sharon Cohen, MD, FRCPC
August 21st 2024The medical director of the Toronto Memory Program at the University of Toronto gave clinical perspective on the promise of mivelsiran, an investigational RNA interference therapeutic, and the idea behind using RNA therapies to treat Alzheimer disease. [WATCH TIME: 5 minutes]
NeuroVoices: Anthony Caggiano, MD, PhD, on Therapeutic Progress of Alzheimer Agent CT1812
August 21st 2024The chief medical officer and head of Research & Development at Cognition Therapeutics discussed data from the phase 2 proof-of-concept SHINE study assessing CT1812, a small molecule oligomer antagonist, in early-stage Alzheimer disease.
Promising Diagnostic Approaches Emerging for Brain Pathologies: James Leverenz, MD
August 16th 2024The director of the Cleveland Lou Ruvo Center for Brain Health at Cleveland Clinic discussed new diagnostic techniques that show promise for advancing the understanding of brain pathologies like Alzheimer and Lewy Body diseases. [WATCH TIME: 3 minutes]
Potential of Newer Techniques to Diagnose Dementia with Lewy Bodies: James Leverenz, MD
August 15th 2024The director of the Cleveland Lou Ruvo Center for Brain Health at Cleveland Clinic talked about challenges of accurately diagnosing dementia with Lewy bodies as well as new methods that show promise in guiding treatment. [WATCH TIME: 3 minutes]
Challenges in Early Diagnosis of Frontotemporal Dementia in Clinical Settings: Chris Berka
August 13th 2024The CEO and cofounder at Advanced Brain Monitoring talked about how the early diagnosis of frontotemporal dementia is often mistaken for Alzheimer disease, but advancements in neuropsychological assessments and biomarker identification may improve accuracy. [WATCH TIME: 4 minutes]
Tracking Neurodegenerative Disease Trajectories With EEG Biomarkers: Chris Berka
August 11th 2024The CEO and cofounder at Advanced Brain Monitoring discussed using EEG-based biomarkers to identify early markers that predict cognitive decline and aid in differential diagnosis for neurodegenerative diseases. [WATCH TIME: 4 minutes]
Adapting to Changes in Alzheimer Disease Trials and Therapeutics: Ivana Rubino, PhD, MSc
August 8th 2024The head of Global Medical for Neuropsychiatry and Alzheimer Disease at Biogen commented on challenges with conducting effective trials for Alzheimer disease and the potential research opportunities with newly approved novel treatments. [WATCH TIME: 6 minutes]
Insights From a Large-Scale Study on Differentiating Dementia Subtypes With EEG: Chris Berka
August 8th 2024The CEO and cofounder at Advanced Brain Monitoring talked about how exploring electroencephalography patterns can help differentiate between Alzheimer disease, Lewy body dementia, and frontotemporal dementia. [WATCH TIME: 3 minutes]
Impact of Blood Tests on Wait Times and Treatment in Alzheimer Disease: Soeren Mattke, MD, DSc
August 7th 2024The director of the Brain Health Observatory at the University of Southern California discussed how blood tests for Alzheimer disease could significantly reduce diagnostic wait times and improve treatment monitoring. [WATCH TIME: 4 minutes]
Mechanism of Action and Potential of Anti-Tau Agent BIIB080: Ivana Rubino, PhD, BSc
August 6th 2024The head of Global Medical for Neuropsychiatry and Alzheimer Disease at Biogen provided perspective on the promising development of BIIB080, a treatment thought to work by reducing forms of tau protein. [WATCH TIME: 4 minutes]