Latest Conference Coverage

Ocrelizumab Has Long-Term, Positive Effects on MS Symptoms, Productivity

The results demonstrate a positive change in patients with previous disease-modifying drug failures.

Quality of Life Improved Significantly Following Wellness Program for Multiple Sclerosis

Patient data were evaluated over a 3-year period, with analyses from baseline, year 1, and year 2 presented at previous CMSC meetings.

Swank, Wahls Diets May Reduce Fatigue and Cognitive Dysfunction in MS

Both diets resulted in patients with MS reporting significant changes on Perceived Deficits Questionnaire scores for fatigue and cognitive dysfunction after 12 weeks of intervention.

ECTRIMS 2021: Key Takeaways, Data Highlights, and Ongoing Research

The NeurologyLive staff compiled highlights from our discussions with experts in one convenient location, following ECTRIMS 2021.

Telehealth and Integrative Medicine for Multiple Sclerosis: Megan Weigel, DNP, APRN-C, APHN-C, MSCN

Discussing a 6-week, virtual program conducted over Zoom, the founder of First Coast Integrative Medicine, spoke on the use of telehealth and future research efforts for integrative medicine in MS. [WATCH TIME: 3 minutes]

Episode 49: Altering the View of MS With a Topographical Model

"Mind Moments," a podcast from NeurologyLive, brings you an exclusive interview with Stephen Krieger, MD.

Cleveland Clinic: Institutional Perspectives in Neurology, Chaired by Devon Conway, MD

Chaired by Devon Conway, MD, the presentations also feature Cleveland Clinic experts Kedar Mahajan, MD, PhD; Marisa McGinley, DO; and Amy Kunchok, MD. [WATCH TIME: 1 hour, 33 minutes]

Discussing the Need for Patient Monitoring After Stopping Multiple Sclerosis Treatment

Deborah Miller, PhD, commented on strategies to maintain patient-provider communication following the discontinuation of disease-modifying therapies in MS.

‘Inspire MS’ and Integrative Medicine for Multiple Sclerosis: Megan Weigel, DNP, APRN-C, APHN-C, MSCN

The founder of First Coast Integrative Medicine spoke on a 6-week virtual program that introduced IM modalities, including guided journaling, nutrition, and yoga. [WATCH TIME: 3 minutes]

Long-Term Ocrelizumab, Satralizumab Data Offer Insights into MS and NMOSD Care

Ashish Pradhan, MD, the executive director and disease area lead for MS and NMOSD, Genentech, offered insight on a number of presentations at the 2021 ECTRIMS Congress.

Advances in MS Treatment, ECTRIMS 2021 Takeaways: Lawrence Steinman, MD

Discussing this year’s virtual ECTRIMS conference, the Zimmermann Professor of Neurology and Neurological Sciences, and Pediatrics at Stanford University provided his opinion on recent developments in the MS field. [WATCH TIME: 3 minutes]

Impact of Ublituximab for Patients With Relapsing MS: Lawrence Steinman, MD

The Zimmermann Professor of Neurology and Neurological Sciences, and Pediatrics at Stanford University discussed the treatment’s potential in the multiple sclerosis space, where there are other competing drugs with similar safety profiles. [WATCH TIME: 4 minutes]

The Value of Integrative Medicine Approaches for Multiple Sclerosis

Megan Weigel, DNP, APRN-C, APHN-C, MSCN, discussed findings from a study of integrative medicine via a virtual, 6-week workshop, which produced varied results.

Treating the Root of Multiple Sclerosis With ATA188: Bridget A. Bagert, MD, MPH

After showing potential remyelination effects, the director of the Multiple Sclerosis Center at Ochsner Health offered her perspective on the latest data for ATA188 in progressive MS. [WATCH TIME: 4 minutes]

Assessing Antibody, Cellular Response to COVID-19 Vaccines in Ocrelizumab-Treated Patients: Ilya Kister, MD

The professor of neurology at the NYU Grossman School of Medicine discussed the trial design of VIOLA, a new prospective study evaluating responses to COVID-19 vaccines in patients with MS on ocrelizumab (Ocrevus; Genentech). [WATCH TIME: 3 minutes]

Epidemiologic and Clinical Highlights in MS Care From ECTRIMS 2021

In the final day’s plenary session at ECTRIMS Congress, Ruth Ann Marrie, MD, PhD, FRCPC, FCAHS, gave a look into some of the notable presentations from the annual meeting.

Eculizumab Shows Better Prolonging of Time to NMOSD Relapse Than Other Treatments

An indirect comparison study evaluated relative treatment effects of eculizumab (Soliris; Alexion), inebilizumab (Uplizna; Horizon), and satralizumab (Enspryng; Genentech), the 3 FDA-approved options for NMOSD.

Integrative Medicine Workshop Produces Varied Results in Wellness, Self-Efficacy in MS

The workshop included weekly virtual meetings on journaling, meditation, yoga therapeutics, among other activities.

Alemtuzumab Treatment Poplation Identified, Siponimod Preserves Retinal Thickness, ATA188 Shows Success in Phase 1

Neurology News Network for the week ending October 15, 2021. [WATCH TIME: 3 minutes]

Worsening Disability in Children With MS Predicted By Clinico-Demographic Characteristics

Investigators concluded that treatment with high-efficacy disease-modifying therapies was a protective factor in disease prognosis.

Expanded Data from ULTIMATE 1 and 2 Trials of Ublituximab: Lawrence Steinman, MD

The Zimmermann Professor of Neurology and Neurological Sciences, and Pediatrics at Stanford University spoke on the safety and efficacy of ublituximab in treating patients with relapsing forms of multiple sclerosis. [WATCH TIME: 4 minutes]

Stable Immunity Observed After COVID-19 Infection in Patients With Multiple Sclerosis

Data presented at the ECTRIMS Congress 2021 noted immunity was reduced in patients taking anti-CD20 monoclonal antibodies.

Targeting Epstein-Barr Virus–Infected B Cells With ATA188: Bridget A. Bagert, MD, MPH

The director of the Multiple Sclerosis Center at Ochsner Health discussed the open-label extension data presented at ECTRIMS Congress on ATA188 in progressive MS. [WATCH TIME: 4 minutes]

Real-World Ofatumumab Use Highlighted Post-Approval for MS

The vast majority of patients with MS, 63.4%, who initiated ofatumumab treatment in the 6 months after its approval had mild disability, while only 29.2% had moderate disability and 7.4% had severe disability.

Nabiximols Shows Continued Impact on Spasticity in Multiple Sclerosis

The treatment effect observed from nabiximols (Sativex; GW Pharmaceuticals) was significant at all 1-week time points over the course of the 12-week study.

Expanded Data, Future Implications for Ublituximab in Relapsing Multiple Sclerosis

Lawrence Steinman, MD, Zimmermann Professor of Neurology and Neurological Sciences, and Pediatrics at Stanford University, discussed findings presented at ECTRIMS 2021.

Siponimod Demonstrates Beneficial Effects on Neurodegeneration in Progressive MS

Data from the EXPAND trial show that after 12 months of treatment, changes on retinal nerve fiber layer thickness favored those on siponimod rather than the placebo group.

Grading Valuable Aspects of Mesenchymal Cell Activity in Progressive MS: Jeffrey Cohen, MD

The director of the Mellen Center for MS Treatment and Research at Cleveland Clinic provided context on whether efficacy outcomes should be weighed more than mechanistic action when evaluating MSC-NTF cell therapies. [WATCH TIME: 3 minutes]

ATA188 Shows Sustained Benefit in Progressive MS in Phase 1 Extension Study

In addition to the data presented at ECTRIMS Congress 2021, Atara Bio is investigating the therapy in an ongoing and enrolling phase 2 study, EMBOLD (NCT03283826), which is expected to read out interim results in early 2022.

Pfizer COVID-19 Vaccine Safe for Patients With Multiple Sclerosis

After vaccination, patients showed no increased risk of relapse activity, but had varied immune response depending on the disease-modifying therapy they were treated with.