Expanding Genetic Associations Between Races and Alzheimer Disease: Margaret Pericak-Vance, PhD
July 18th 2022The director of the John P. Hussman Institute for Human Genomics at the University of Miami discussed non-APOE–related genetic correlations between different groups of individuals and Alzheimer disease. [WATCH TIME: 5 minutes]
Technological Advancements Improving, Expanding Capabilities of Antibody Testing: Sean Pittock, MD
July 17th 2022The director of the Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology discussed the technological capabilities the center has, including the improved use of neural antibody testing. [WATCH TIME: 6 minutes]
The Role of Genetics in Alzheimer Drug Development: Margaret Pericak-Vance, PhD
July 15th 2022The director of the John P. Hussman Institute for Human Genomics at the University of Miami provided insight on the outlook on genetics and gene-based therapies for Alzheimer disease. [WATCH TIME: 3 minutes]
Realistic Expectations and Limitations in MS Rehab With Exoskeletons: Francois Bethoux, MD
July 14th 2022The chair of Cleveland Clinic’s Department of Physical Medicine discussed the different ways a newly approved robotic exoskeleton can improve gait in patients with multiple sclerosis. [WATCH TIME: 4 minutes]
Drawing From Experience When Treating Parkinson Disease: Temitope Lawal, MD
July 14th 2022The neurologist and movement disorders fellow at University Hospitals Cleveland Medical Center spoke about how his experience as a caregiver shapes his perspective as a doctor in care for those with movement disorders. [WATCH TIME: 3 minutes]
Repurposed Noradrenergic Drugs Show Small Benefits in Alzheimer Disease Cognition, Apathy
July 14th 2022In a meta-analysis spanning 10 studies of 1300 patients with Alzheimer disease, global cognition, as measured by the Mini-Mental State Examination or ADAS-Cog, was improved using noradrenergic drugs.
Muscle-Directed Therapy Apitegromab Reports Positive 24-Month Results in Spinal Muscular Atrophy
July 12th 2022Over a 2-year period, apitegromab-treated patients demonstrated sizable and sustained improvements in Hammersmith Functional Motor Scale-Expanded and substantial increases in Revised Upper Limb Module scores.
Working With Interdisciplinary Teams in Movement Disorders: Temitope Lawal, MD
July 12th 2022The neurologist and movement disorders fellow at University Hospitals Cleveland Medical Center shared his experiences engaging with a diverse community of clinicians at the ATMRD Congress and in clinical practice. [WATCH TIME: 2 minutes]
Alzheimer Disease Risk Improved Through Major Lifestyle Factors Regardless of Socioeconomic Status
July 12th 2022The risk of developing Alzheimer disease and related dementias decreased gradually with increasing scores in a dose-response manner on a model geared toward identifying healthy lifestyle factors.
Peers & Perspectives: The Induction vs Escalation Approach to MS and the TREAT-MS Trial
July 12th 2022Scott Newsome, DO, and Ellen Mowry, MD, discuss the ongoing TREAT-MS trial and its goals, the importance of the findings for clinical practice in multiple sclerosis, and the ongoing discussion around induction vs escalation in MS treatment. [WATCH TIME: 24 minutes]
Biohaven Commences Phase 3 Study of Taldefgrobep Alfa in Spinal Muscular Atrophy
July 11th 2022Taldefgrobep alfa, a muscle-targeted experimental treatment potentially used in combination with other SMA therapies, will be evaluated in a cohort of 180 patients with SMA, regardless of ambulatory status or disease classification.
EEG Changes in Acute Phase of Autoimmune Encephalitis May Predict Risk of Drug-Resistant Epilepsy
July 10th 2022Of the patients with drug-resistant epilepsy in the cohort, 54% had status epilepticus during their acute admission, and 2 of 3 patients with NORSE ended up developing drug-resistant epilepsy at 12 months.