Efficacy, Safety of Rimegepant When Used Both as Preventively and As-Need: Richard B. Lipton, MD
July 10th 2022The director of the Montefiore Headache Center provided insight on an open-label study presented at AHS 2022 that highlighted rimegepant’s (Nurtec ODT; Biohaven) impact both as a preventative and acute medication. [WATCH TIME: 5 minutes]
FDA Places Clinical Hold on Phase 2/3 ReMEDy2 Trial of DM199 in Acute Ischemic Stroke
July 9th 2022After 3 instances of clinically significant, transient hypotension—which resolved after treatment halt—recruitment for the trial of the investigational recombinant KLK1 tissue protein has been paused.
Understanding Individual Risks, Improving Trial Designs for Sleep Disorders in Alzheimer Disease
July 7th 2022Ruth Benca, MD, PhD, a professor and the chair of Psychiatry & Human Behavior at Wake Forest School of Medicine, provided insight on the age- and sex-related differences in sleep disorders, and the needed research on the effects of therapeutics in older populations.
Advocating for Patients With Migraine Through Research Initiatives: Serena L. Orr, MD, MSc
July 7th 2022The pediatric neurologist and headache specialist at the University of Calgary and Alberta Children’s Hospital spoke about the need for improved funding and research efforts for the migraine population. [WATCH TIME: 5 minutes]
NeurologyLive® Top Expert Interviews: June 2022
July 7th 2022Expert clinicians offer their insight on the sleep disorder landscape, the state of mental health in pediatric migraine, an inaugural movement disorders congress, a novel stroke rehabilitation tool, and psychedelics in cluster headache.
FDA Accepts BLA for Lecanemab in Alzheimer Disease, Sets PDUFA Date for January 2023
July 7th 2022In addition to filing under the accelerated approval pathway, Eisai will submit for a traditional approval of lecenamab before the end of the first quarter of 2023, seeking an indication for mild cognitive impairment because of Alzheimer disease.
Learning From Patients With Parkinson Disease: Laxman Bahroo, DO
July 6th 2022The assistant professor of neurology and codirector of the Neurology Residency Program at MedStar Georgetown University Hospital and presenter at ATMRD offered his insight into the benefits of multispecialty meetings. [WATCH TIME: 1 minute]
NeuroVoices: Francois Bethoux, MD, on Innovating MS Rehabilitation With the EksoNR Exoskeleton
July 6th 2022The chair of Cleveland Clinic’s Department of Physical Medicine discussed a new rehabilitative approach using a robotic exoskeleton to improve fatigue and gait in patients with multiple sclerosis.
Presence of MOG-IgG in Children Meeting MS Criteria May Allude to Nontypical Disease Course
July 5th 2022All 12 of the children met diagnostic criteria for multiple sclerosis and were seropositive for MOG-IgG at baseline experienced a disease course different than typical MS through the observed time.
Distinguishing and Diagnosing Various Presentations of Autoimmune Encephalitis: Sean Pittock, MD
July 5th 2022The director of the Mayo Clinic Center for Multiple Sclerosis and Autoimmune Neurology discussed the complexities in diagnosing autoimmune encephalitis and the approach needed to be taken. [WATCH TIME: 5 minutes]
Biogen, Alectos Announce Licensing Agreement for Parkinson Disease GBA2 Inhibitor AL01811
July 5th 2022Alectos to receive a $15 million upfront payment from Biogen and is eligible to receive upward of $630 million pending the success of the collaboration and achieving future milestones for the investigational PD treatment.
Properly Assessing Cognition in Patients With Multiple Sclerosis: John DeLuca, PhD
July 4th 2022The senior vice president for research and training at the Kessler Foundation discussed the assessment of cognitive challenges among patients with multiple sclerosis and planning for treatment options when necessary. [WATCH TIME: 4 minutes]
Assessing Early Evidence, Long-Term Potential of EksoRN Robotic Exoskeleton: Francois Bethoux, MD
July 3rd 2022The chair of Cleveland Clinic’s Department of Physical Medicine detailed a pilot study on the rehabilitative impacts of the EksoRN robotic exoskeleton in patients with multiple sclerosis. [WATCH TIME: 5 minutes]
Improvements in Treating Narcolepsy, Idiopathic Hypersomnia Through Xywav
July 2nd 2022Richard Bogan, MD, FCCP, FAASM, associate clinical professor, University of South Carolina School of Medicine, provided commentary on multifunctional capabilities of Xywav and how the medication has improved care for narcolepsy and idiopathic hypersomnia.