FDA Issues Discipline Review Letter for ADAM Zolmitriptan NDA in Acute Migraine
October 1st 2020Zosano Pharma noted that the DRL does not reflect the final FDA decision on the application, though the approval of zolmitriptan by its PDUFA action date of October 20, 2020, is no longer likely as a result.
Transient Orthostatic Hypotension Appears Common in Parkinson Disease
September 30th 2020The investigators noted that continuous non-invasive blood pressure monitoring upon standing may aid in the identification of a modifiable risk factor for syncope-related falls in patients with Parkinson disease.
Intensive Blood Pressure Reduction Linked to More Neurological Deterioration
September 29th 2020Post hoc analysis of the ATACH-II trial suggest that intensive lowering of systolic blood pressure in individuals with initial levels ≥220 mmHg increases the rate of neurological deterioration over 24 hours.
Costantino Iadecola, MD: Awareness of Vascular Risk Factors in Alzheimer Disease
September 29th 2020The director of the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine discussed the role amyloid plays in various types of Alzheimer disease and its impact on vascular dysfunction.