Gait Changes Can Predict Parkinson Conversion From Prodromal Phase
August 6th 2019The professor of neurology at University Medical Center Schleswig‐Holstein, and member of the department of neurodegenerative diseases at University Hospital Tübingen shared insight into the quantitative gait characteristics measured by wearable devices which can play an important role in the identification of prodromal Parkinson disease and its progression.
Galcanezumab Reduces Monthly Migraine Days in Episodic, Chronic Migraine
August 5th 2019The findings demonstrated that the galcanezumab group—made up of those with both chronic and episodic migraine—experienced a 4.1-day reduction in monthly migraine headache days compared to a 1.0-day reduction with placebo.
Sarah Wilson, PhD: Managing Post-Operative Patients With Epilepsy
August 5th 2019The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne detailed how the transition from states of illness to wellness after epilepsy surgery can result not just in brain changes, but psychosocial challenges for patients.
Can Telemedicine Make a Difference in Neurology Subspecialties?
August 5th 2019The staff neurologist at Cleveland Clinic’s Mellen Center for MS shared her insight into the use of telemedicine in an outpatient setting across a number of subspecialties in neurology and how it can supplement care going forward.
Gene Therapy for CLN6 Batten Disease Shows Positive Interim Results
August 3rd 2019Interim data from the first 8 pediatric patients showed that the AAV-CLN6 gene therapy demonstrated a positive impact on motor and language function compared to a natural history dataset, as well as in comparison to in-study sibling pairs.
Impacting Pediatric Stroke Care By Raising Physician Awareness
August 3rd 2019The director of the Pediatric Stroke Program at CHOP spoke about the need to improve early recognition of pediatric stroke and physician awareness of the condition, which many believe is underdiagnosed and underestimated.
What Role Do Genetics Play in Determining Alzheimer Disease Risk?
August 2nd 2019The professor of neurology and founding chair of the John T. Macdonald Foundation Department of Human Genetics at the University of Miami discussed the distinctions between Alzheimer disease risk of ethnicities that share genetic markers.
Noah Rosen, MD: Evaluation of Cardiovascular Risks of Galcanezumab in Episodic, Chronic Migraine
August 2nd 2019The program director of neurology at the Zucker School of Medicine, Northwell Health, spoke about the great advances of the new CGRP medications available for the prevention of migraine.
Sarah Wilson, PhD: The Burden of Normality Post-Epilepsy Surgery
August 2nd 2019The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne spoke about what physicians need to provide to help patients through the adjustment period after epilepsy surgery.
Sarah Wilson, PhD: The Promise of Neurorehabilitation After Epilepsy Surgery
August 1st 2019The clinical neuropsychologist and head of the School of Psychological Sciences at the University of Melbourne discussed the early-stage research into neurorehabilitation post-epilepsy surgery, and the promise it might hold to address surgery’s long-term risks.
Genetic Testing Program for hATTR Expanded
August 1st 2019One year post-launch, the Ambry Genetics and Akcea Therapeutics hereditary ATTR amyloidosis testing program has been used by more than 700 physicians. The free test screens for up to 81 genes that cause hereditary polyneuropathies and up to 92 genes associated with hereditary cardiomyopathies, including hATTR amyloidosis.
Early MRI Scans Can Predict Long-Term Disease Outcomes in Relapse-Onset Multiple Sclerosis
July 31st 2019Early focal inflammatory disease activity and spinal cord lesions are predictors of long-term disease outcomes, which may be useful in counseling patients and personalizing treatment plans.
Wearable-Detected Gait Changes Predict Parkinson Disease Conversion
July 31st 2019At usual-speed walking, a number of domains of gait variability, pace, asymmetry, and postural control were significantly predictive of conversion to Parkinson disease, and could be used in combination with markers to identify prodromal disease and its progression.
Tic Suppression Ability Predicts Future Symptom Outcomes
July 31st 2019Investigators found reductions in tic frequency and increases in the number of tic-free intervals when children were merely asked verbally to suppress their tics, and when an immediate and contingent reward was delivered for successful tic suppression, tic suppression was enhanced.
sTMS Proves Safe, Effective for Migraine With Medication Overuse
July 30th 2019The use of single-pulse transcranial magnetic stimulation, while already FDA-approved for acute and preventive migraine treatment, has shown that it can be effective in reducing the need for acute headache medications in patients with migraine.
Dawn Buse, PhD: Inappropriate Prescriptions in Acute, Preventive Migraine Treatment
July 30th 2019The clinical professor of neurology at Albert Einstein College of Medicine spoke to the findings of the OVERCOME study, and how recent literature has suggested that improper prescriptions and medication use in migraine have been ongoing in spite of the current recommendations.
Phase 3 Study of Fenfluramine in Lennox-Gastaut Syndrome Completes Enrollment
July 30th 2019Zogenix has announced that its Study 1601 of fenfluramine (Fintepla), also known as ZX008, in the treatment of seizures associated with Lennox-Gastaut syndrome has completed enrollment and is on schedule to report top-line data in Q1 2020.
Intensive Blood Pressure Lowering Is Likely to Reduce Stroke Recurrence
July 30th 2019Despite the fact that the rate of reductions for recurrent stroke in the intensive group were not significant in this study, a meta-analysis of 3 previous trials supports the use of a blood pressure target less than 130/80 mm Hg to reduce stroke recurrence.
David Wolk, MD: Utilizing MRI in Alzheimer Disease
July 29th 2019The co-director of the University of Pennsylvania Memory Center will share additional insights on Alzheimer disease at the upcoming International Congress on the Future of Neurology, taking place September 27-28, 2019 in New York City.
Neuromodulation Shows Early Success in Epilepsy Treatment
July 29th 2019The University of Alabama at Birmingham neuromodulation epilepsy clinic has treated 43 patients with drug-resistant epilepsy, reducing seizures by >60% for a number of patients with both vagus nerve stimulation and responsive neurostimulation techniques.