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Videos

At ECTRIMS 2024, the assistant professor at the University of Naples the latest multiple sclerosis diagnostic criteria, which emphasized a shift toward biologically based diagnoses. [WATCH TIME: 4 minutes]

Bridging Clinical Signs and Biological Evidence to Transform MS Diagnosis: Marcello Moccia, MD, PhD

Articles

A new study highlighted the importance of initiating immunotherapy promptly in chronic inflammatory demyelinating polyneuropathy to prevent axonal damage and disability progression.

Early Immunotherapy May Be Crucial to Prevent Axonal Damage in CIDP, Study Suggests

At the 2024 ECTRIMS Congress, the neurologist at the University Hospital Center of Nice talked about how the decision to treat patients at risk of MS is highly individualized. [WATCH TIME: 3 minutes]

Navigating the Decision to Treat Multiple Sclerosis Early Versus Later: Mikael Cohen, MD

Here's some of what is coming soon to NeurologyLive® this week. 

This Week on NeurologyLive® — January 20, 2024

The neurologist and sleep disorder specialist at Allegheny Health Network discussed the challenges with preventing narcolepsy and the strategies patients can take to improve their overall prognosis. [WATCH TIME: 4 minutes]

Curving Complications Associated With Narcolepsy: Mihaela Nowak, MD

Marco Meglio, Assistant Managing Editor for 

, has been with the team since October 2019. Follow him on Twitter 

The professor and chair of the Department of Molecular Pathobiology at NYU College of Dentistry discussed groundbreaking research on chronic pain, focusing on the discovery of new mechanisms involving nerve growth factor and its receptors.

NeuroVoices: Nigel Bunnett, PhD, BSc, on Identifying a Novel Therapeutic Target for Chronic Pain

Founding director of the Optimal Aging Institute at the NYU Grossman School of Medicine.

The founding director of the Optimal Aging Institute at the NYU Grossman School of Medicine talked about a recent study that estimated the lifetime risk of dementia and its implications for prevention, care, as well as societal planning. [WATCH TIME: 5 minutes]

Understanding Lifetime Risk and the Rising Burden of Dementia: Josef Coresh, MD, PhD

James Wheless, MD, FAAP, FAAN, FAES, Le Bonheur Chair in Pediatric Neurology at the University of Tennessee Health Science Center, shared insights on his presentation from AES 2024, focusing on stiripentol, an FDA-approved treatment for Dravet syndrome.

Optimizing Epilepsy Treatments: Stiripentol’s Role in Dravet Syndrome

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Expert Perspectives on Dravet Syndrome Management

Clinical

Expert Dravet Syndrome Overview

Video content above is prompted by the following:

Please describe disease prevalence and common symptoms patients may experience.

At what age do patients present with their first seizure or other symptoms?

How does the disease manifest in patients as they age?

Scott Perry, MD, discusses how Dravet syndrome, a rare genetic epilepsy, presents significant challenges in diagnosis, treatment, and management, emphasizing the importance of early detection, comprehensive care strategies, and support for both patients and caregivers to optimize outcomes and quality of life.

Scott Perry, MD, discusses how Dravet syndrome is a rare genetic epilepsy characterized by frequent, prolonged seizures beginning in infancy, often accompanied by developmental delays and other health issues that persist and evolve as patients age.

Scott Perry, MD, discusses how Dravet syndrome is diagnosed through a combination of clinical observation, genetic testing, and phenotypic evaluation, emphasizing the challenges and importance of early diagnosis to improve patient outcomes.

Dravet Syndrome Diagnosis

Scott Perry, MD, discusses how pediatric patients with Dravet syndrome often experience various comorbidities alongside seizures, including developmental delays, behavioral issues, and sleep disturbances, which significantly impact quality of life, especially when diagnosis is delayed, necessitating comprehensive management strategies.

Dravet Syndrome: Comorbidities and Patient Quality of Life

The panelist discusses how the goal of Dravet syndrome treatment is to reduce seizure frequency and severity, typically starting with initial treatments like valproate and clobazam and potentially escalating to combination therapies including options such as cannabidiol, with the overall aim of improving patients’ quality of life and developmental outcomes

Current Treatment Options for Dravet Syndrome

Scott Perry, MD, discusses how treatment challenges in Dravet syndrome necessitate careful monitoring by health care providers, who must consider factors such as individual patient response, adverse effect profiles, drug interactions, and the potential need for escalation therapy, to optimize seizure control and overall patient outcomes.

Challenges Associated With Dravet Syndrome Treatment

Scott Perry, MD, discusses how caregivers of patients with Dravet syndrome face significant challenges and emphasizes the importance of health care providers navigating sensitive conversations with empathy, clear communication, and comprehensive support to address caregivers’ concerns and needs.

Dravet Syndrome and Caregiver Burdens

Scott Perry, MD, discusses how effective management of Dravet syndrome requires a multidisciplinary approach, emphasizing the critical importance of early diagnosis and aggressive treatment aimed at achieving seizure freedom, which can significantly improve long-term outcomes and quality of life for patients.

Final Thoughts on Dravet Syndrome Management

Lasso - DMD Peers and Perspectives NSP-21-NRD0157

 video series brings together pairs of expert clinicians and physicians to independently provide their insights on the latest and most up-to-date clinical care for specific neurologic diseases and disorders.

Expert Dravet Syndrome Overview

EP: 1.Expert Dravet Syndrome Overview

EP: 2.Dravet Syndrome Diagnosis

EP: 3.Dravet Syndrome: Comorbidities and Patient Quality of Life

EP: 4.Current Treatment Options for Dravet Syndrome

EP: 5.Challenges Associated With Dravet Syndrome Treatment

EP: 6.Dravet Syndrome and Caregiver Burdens

EP: 7.Final Thoughts on Dravet Syndrome Management